Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 3/20 | 0.74 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.65 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.65 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
| ▸ | DRD4 | P21917 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.61 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.61 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.61 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.61 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.61 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.61 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4915838 | 0.92 | TSHR (0.64) | CCR3MCHR1SLC6A12TMEM97SIGMAR1 | |
| SCHEMBL4918016 | 0.85 | CCR3 (0.66) | CCR3MCHR1DRD4TSHRHRH3 | |
| SCHEMBL4916472 | 0.85 | TSHR (0.60) | CCR3TSHRKMT2AMEN1 | |
| SCHEMBL4916477 | 0.85 | TSHR (0.60) | CCR3MCHR1TSHRPRKAA2PRKAB2 | |
| SCHEMBL4922789 | 0.85 | TSHR (0.60) | CCR3MCHR1TSHRHRH3KMT2A | |
| SCHEMBL9872559 | 0.83 | DRD4 (0.78) | CCR3MCHR1SIGMAR1DRD4KMT2A | |
| SCHEMBL5577635 | 0.82 | TSHR (0.71) | MCHR1DRD4TSHRHRH3KMT2A | |
| SCHEMBL5577499 | 0.82 | CHRM3 (0.58) | CCR3MCHR1DRD4TSHRKMT2A | |
| SCHEMBL4916465 | 0.82 | TSHR (0.56) | CCR3TSHRPRKAA2PRKAB2PRKAG1 | |
| SCHEMBL4916458 | 0.82 | TSHR (0.56) | CCR3TMEM97TSHRCHRM1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080081824-A1 | Substituted piperidines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY | 2008-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081824-A1 | Substituted piperidines as modulators of chemokine receptor activity | CCR1, CCR3, CCR2 | CCR3 2/4885MCHR1 358/4885SLC6A12 4344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.