Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CCR3 | P51677 | 1/20 | 0.54 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.48 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.48 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.48 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.48 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.48 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.48 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4924140 | 0.89 | ALDH1A1 (0.59) | TSHRCACNA1GSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4915838 | 0.85 | TSHR (0.64) | TSHRCCR3CACNA1GSMN1; SMN2MEN1 | |
| SCHEMBL4915835 | 0.85 | CCR3 (0.74) | TSHRCCR3MEN1KMT2APRKAB2 | |
| SCHEMBL4922782 | 0.81 | TSHR (0.55) | TSHRCCR3CACNA1GSMN1; SMN2NPC1 | |
| SCHEMBL4922789 | 0.81 | TSHR (0.60) | TSHRCCR3CACNA1GSMN1; SMN2NPC1 | |
| SCHEMBL4916472 | 0.81 | TSHR (0.60) | TSHRCCR3CACNA1GSMN1; SMN2MEN1 | |
| SCHEMBL4920750 | 0.81 | TSHR (0.53) | TSHRCCR3CACNA1GSMN1; SMN2NPC1 | |
| SCHEMBL4914266 | 0.81 | LMNA (0.54) | TSHRSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL4921760 | 0.81 | TSHR (0.55) | TSHRCCR3CACNA1GSMN1; SMN2ACKR3 | |
| SCHEMBL4916458 | 0.80 | TSHR (0.56) | TSHRCCR3CACNA1GSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080081824-A1 | Substituted piperidines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY | 2008-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081824-A1 | Substituted piperidines as modulators of chemokine receptor activity | CCR1, CCR3, CCR2 | TSHR 727/4885CCR3 2/4885CACNA1G 1431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.