Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746932 | 0.95 | CES1 (0.46) | CES1GPR35PTPRCNOTUMKDM4E | |
| Ammonia Solution, Strong SCHEMBL6102503 | 0.94 | CES1 (0.44) | CES1GPR35PTPRCNOTUMKDM4E | |
| SCHEMBL6992698 | 0.85 | CES1 (0.46) | CES1PTPRCKDM4EALDH1A1HPGD | |
| SCHEMBL14269133 | 0.84 | OPRD1 (0.49) | CES1PTPRCKDM4EALDH1A1HPGD | |
| SCHEMBL14294472 | 0.81 | CES1 (0.42) | CES1PTPRCKDM4EALDH1A1HPGD | |
| SCHEMBL6998703 | 0.81 | CES1 (0.44) | CES1PTPRCKDM4EALDH1A1HPGD | |
| SCHEMBL14269132 | 0.80 | OPRD1 (0.48) | CES1PTPRCKDM4EALDH1A1HPGD | |
| SCHEMBL4839262 | 0.80 | CES1 (0.43) | CES1PTPRCPABPC1DNMT1 | |
| SCHEMBL14269128 | 0.78 | STAT3 (0.43) | CES1PTPRCALDH1A1GAA | |
| SCHEMBL4829987 | 0.78 | STAT3 (0.43) | CES1PTPRCALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332615-B2 | Hydrophilic analogs of 4,8-dihydrobenzodithiophene-4,8-diones as anticancer agents | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2008-02-19 | — | — | US | disclosed |
| US-7332615-B2 | Hydrophilic analogs of 4,8-dihydrobenzodithiophene-4,8-diones as anticancer agents | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2008-02-19 | — | — | US | disclosed |
| US-7332615-B2 | Hydrophilic analogs of 4,8-dihydrobenzodithiophene-4,8-diones as anticancer agents | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2008-02-19 | — | — | US | disclosed |
| US-20060069041-A1 | Novel hydrophilic analogs of 4,8-dihydrobenzodithiophene-4,8-diones as anticancer agents | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2006-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069041-A1 | Novel hydrophilic analogs of 4,8-dihydrobenzodithiophene-4,8-diones as anticancer agents | ABCG2, ABCC8, ABCB1 | CES1 3292/4885GPR35 3244/4885PTPRC 2181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.