Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GRM5 | P41594 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11883827 | 0.88 | APP (0.44) | APPMAPTGRM5 | |
| SCHEMBL21858022 | 0.85 | CYP1A2 (0.56) | APPMAPTGRM5CYP1A2CYP3A4 | |
| SCHEMBL5184857 | 0.85 | APP (0.55) | APPMAPTGRM5TSHRCYP1A2 | |
| Diphenylacetylene SCHEMBL28323591 | 0.82 | APP (0.86) | APPMAPTGRM5TSHRCYP1A2 | |
| Diphenylacetylene SCHEMBL68254 | 0.82 | APP (1.00) | APPMAPTGRM5TSHRCYP1A2 | |
| Diphenylacetylene SCHEMBL960609 | 0.82 | APP (1.00) | APPMAPTGRM5TSHRCYP1A2 | |
| Diphenylacetylene SCHEMBL29188592 | 0.82 | APP (1.00) | APPMAPTGRM5TSHRCYP1A2 | |
| Diphenylacetylene SCHEMBL23754282 | 0.78 | APP (0.92) | APPMAPTGRM5TSHRCYP1A2 | |
| Diphenylacetylene SCHEMBL9273707 | 0.78 | APP (0.92) | APPMAPTGRM5TSHRCYP1A2 | |
| Diphenylacetylene SCHEMBL5576302 | 0.78 | APP (0.92) | APPMAPTGRM5TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115724769-B | Method for synthesizing fluorine-containing phenylethynyl phenyl propionitrile liquid crystal compound | 西安瑞联新材料股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-112955422-B | polycyclic compound | 三菱瓦斯化学株式会社 | 2023-08-22 | — | — | CN | claimed |
| CN-115724769-A | Synthetic method of fluorine-containing phenylethynyl phenyl propinonanitrile liquid crystal compound | 西安瑞联新材料股份有限公司 | 2023-03-03 | — | — | CN | claimed |
| CN-109476704-B | Antibacterial cyclic lipopeptides | 港大科桥有限公司 | 2022-08-16 | — | — | CN | claimed |
| CN-109111416-B | Diether dianhydride monomer with phenylethynyl-containing side group and preparation method and application thereof | 吉林大学 | 2022-03-29 | — | — | CN | claimed |
| US-20210355058-A1 | POLYCYCLIC COMPOUNDS | MITSUBISHI GAS CHEMICAL CO (JP) | 2021-11-18 | — | — | US | claimed |
| US-20210340317-A1 | POLYCYCLIC COMPOUNDS | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2021-11-04 | — | — | US | claimed |
| CN-112955422-A | Polycyclic compounds | 三菱瓦斯化学株式会社 | 2021-06-11 | — | — | CN | claimed |
| US-10647746-B2 | Antibacterial cyclic lipopeptides | VERSITECH LIMITED (HK) | 2020-05-12 | — | — | US | claimed |
| WO-2020079225-A1 | POLYCYCLIC COMPOUNDS | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2020-04-23 | — | — | WO | claimed |
| EP-1373358-A1 | LOW DIELECTRIC CONSTANT MATERIALS AND METHODS OF PREPARATION THEREOF | Honeywell International, Inc. (US) | 2004-01-02 | — | — | EP | claimed |
| US-20030229024-A1 | Methods and compounds for inhibiting beta-amyloid peptide release and/or its synthesis | AUDIA JAMES E (US) | 2003-12-11 | — | — | US | claimed |
| WO-2003057749-A1 | ORGANIC COMPOSITIONS | HONEYWELL INTERNATIONAL INC. (US) | 2003-07-17 | — | — | WO | claimed |
| WO-2002081546-A1 | LOW DIELECTRIC CONSTANT MATERIALS AND METHODS OF PREPARATION THEREOF | HONEYWELL INTERNATIONAL INC. (US) | 2002-10-17 | — | — | WO | claimed |
| US-20020052322-A1 | Methods and compounds for inhibiting beta-amyloid peptide release and/or its synthesis | ELAN PHARMACEUTICALS, INC. | 2002-05-02 | — | — | US | claimed |
| US-6191166-B1 | ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. | 2001-02-20 | — | — | US | claimed |
| EP-0942924-A2 | METHODS AND COMPOUNDS FOR INHIBITING $g(b)-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS | Elan Pharmaceuticals, Inc. (US) | 1999-09-22 | — | — | EP | claimed |
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | claimed |
| WO-1998022494-A2 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | ELAN PHARMACEUTICALS, INC. (US) | 1998-05-28 | — | — | WO | claimed |
| US-5674635-A | Electroluminescent device | XEROX CORPORATION (US) | 1997-10-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210340317-A1 | POLYCYCLIC COMPOUNDS | CBR1, C1R, CBR3 | APP 3065/4885MAPT 4484/4885GRM5 2617/4885 |
| US-10647746-B2 | Antibacterial cyclic lipopeptides | NRDC, NGLY1, LNPEP | APP 2250/4885MAPT 4728/4885GRM5 3359/4885 |
| US-20020052322-A1 | Methods and compounds for inhibiting beta-amyloid peptide release and/or its synthesis | APP, BACE1, IAPP | APP 1/4885MAPT 17/4885GRM5 1800/4885 |
| US-20210355058-A1 | POLYCYCLIC COMPOUNDS | CBR1, CBR3, C1R | APP 3100/4885MAPT 4486/4885GRM5 2703/4885 |
| US-20030229024-A1 | Methods and compounds for inhibiting beta-amyloid peptide release and/or its synthesis | APP, BACE1, IAPP | APP 1/4885MAPT 17/4885GRM5 1800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.