Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4923444 | 0.89 | MAPT (0.42) | SMN1; SMN2THRBMAPTNPSR1MEN1 | |
| SCHEMBL4923150 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2THRBMAPTALDH1A1NPSR1 | |
| SCHEMBL4923393 | 0.87 | SMN1; SMN2 (0.45) | SMN1; SMN2THRBMAPTALDH1A1NPSR1 | |
| SCHEMBL4923342 | 0.85 | ELANE (0.37) | SMN1; SMN2THRBMAPTLMNATP53 | |
| SCHEMBL4922493 | 0.83 | SMN1; SMN2 (0.43) | SMN1; SMN2THRBMAPTALDH1A1NPSR1 | |
| SCHEMBL4922512 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2THRBMAPTALDH1A1NPSR1 | |
| SCHEMBL4922481 | 0.78 | MEN1 (0.48) | SMN1; SMN2THRBMAPTALDH1A1NPSR1 | |
| SCHEMBL4916704 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2THRBMAPTALDH1A1NPSR1 | |
| SCHEMBL4922068 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2THRBMAPTALDH1A1NPSR1 | |
| SCHEMBL4922071 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2THRBMAPTALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249091-A1 | Indoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249091-A1 | Indoles Useful in the Treatment of Inflammation | IDO1, IDO2, ARG1 | SMN1; SMN2 3645/4885THRB 639/4885MAPT 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.