Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4922071 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2THRBMEN1KMT2ANPC1 | |
| SCHEMBL4922512 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2THRBMEN1KMT2ATP53 | |
| SCHEMBL4923150 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2THRBMEN1KMT2ATP53 | |
| SCHEMBL4922481 | 0.80 | MEN1 (0.48) | SMN1; SMN2THRBMEN1KMT2ATP53 | |
| SCHEMBL4923393 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2THRBMEN1KMT2ATP53 | |
| SCHEMBL4922493 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2THRBMEN1KMT2ATP53 | |
| SCHEMBL3010897 | 0.77 | SRD5A2 (0.53) | SMN1; SMN2THRBMEN1KMT2ANPC1 | |
| SCHEMBL4916692 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2THRBMEN1KMT2ATP53 | |
| SCHEMBL4916704 | 0.75 | SMN1; SMN2 (0.42) | SMN1; SMN2THRBMEN1KMT2ATP53 | |
| SCHEMBL4920937 | 0.73 | L3MBTL1 (0.50) | SMN1; SMN2THRBMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249091-A1 | Indoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249091-A1 | Indoles Useful in the Treatment of Inflammation | IDO1, IDO2, ARG1 | SMN1; SMN2 3645/4885THRB 639/4885MEN1 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.