SCHEMBL491747

SCHEMBL491747

Cc1ccc([N+](=O)[O-])c(C(=O)Cl)c1

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.58
CYP3A4 P08684 1/20 0.58
MAPT P10636 3/20 0.47
ALDH1A1 P00352 2/20 0.47
POLB P06746 1/20 0.44
GPR35 Q9HC97 1/20 0.44
KCNMA1 Q12791 2/20 0.44
DTYMK P23919 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30440428 1.00 TSHR (0.58) TSHRCYP3A4MAPTALDH1A1POLB
SCHEMBL8494822 0.86 TSHR (0.58) TSHRCYP3A4MAPTALDH1A1POLB
SCHEMBL28395903 0.85 TSHR (0.62) TSHRCYP3A4MAPTALDH1A1POLB
SCHEMBL1277039 0.84 TSHR (0.60) TSHRCYP3A4MAPTALDH1A1POLB
SCHEMBL149316 0.84 DTYMK (0.62) TSHRCYP3A4MAPTALDH1A1POLB
SCHEMBL29935450 0.84 DTYMK (0.62) TSHRCYP3A4MAPTALDH1A1POLB
Hydrochloric Acid SCHEMBL3730916 0.82 DTYMK (0.60) TSHRCYP3A4MAPTALDH1A1POLB
SCHEMBL11048087 0.82 DTYMK (0.60) TSHRCYP3A4MAPTALDH1A1POLB
SCHEMBL8446508 0.82 TSHR (0.58) TSHRCYP3A4MAPTALDH1A1POLB
SCHEMBL688229 0.82 TSHR (0.58) TSHRCYP3A4MAPTALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215040-A1 METHOD AND COMPOUND ATDBio Limited (GB) 2025-07-03 US disclosed
US-20250179572-A1 Photoactive Compounds and Methods for Biomolecule Detection and Sequencing VIBRANT HOLDINGS, LLC 2025-06-05 US disclosed
US-20250042932-A1 METHOD FOR PRODUCING POLYNUCLEOTIDES ATDBio Limited (GB) 2025-02-06 US disclosed
CN-119173522-A Methods and compounds ATD生物有限公司 2024-12-20 CN disclosed
US-12152279-B2 Photoactive compounds and methods for biomolecule detection and sequencing VIBRANT HOLDINGS, LLC (US) 2024-11-26 US disclosed
CN-116200048-B Disperse dye compound containing benzoate groups and application thereof 浙江龙盛集团股份有限公司 2024-08-13 CN disclosed
CN-116200050-B Disperse blue-to-black dye composition and dye product thereof 浙江龙盛集团股份有限公司 2024-08-13 CN disclosed
CN-118339173-A Method for preparing polynucleotide ATD生物有限公司 2024-07-12 CN disclosed
CN-116178982-B Disperse dye compound containing benzoate groups and heterocyclic rings and application thereof 浙江龙盛集团股份有限公司 2024-04-05 CN disclosed
WO-2023180237-A1 METHOD AND COMPOUND ATDBio Limited (GB) 2023-09-28 WO disclosed
EP-0286746-B1 INSECTICIDAL N-(OPTIONALLY SUBSTITUTED) - N'-SUBSTITUTED-N,N'-DISUBSTITUTED- HYDRAZINES ROHM AND HAAS COMPANY (US) 1991-02-27 EP disclosed
EP-0361645-A2 Organic hydrazine derivatives for pharmaceutical use ROHM AND HAAS COMPANY (US) 1990-04-04 EP disclosed
EP-0286746-A1 Insecticidal N-(optionally substituted) - N'-substituted-N,N'-disubstituted- hydrazines ROHM AND HAAS COMPANY (US) 1988-10-19 EP disclosed
EP-0261503-A1 Heterocyclic amido derivatives of substituted benzoic acids and therapeutic compositions which contain them as active principle VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) 1988-03-30 EP disclosed
EP-0086340-B1 3-(1H-TETRAZOL-5-YL)-4(3H)-QUINAZOLINONES THE DOW CHEMICAL COMPANY (US) 1986-04-02 EP disclosed
US-4419357-A 3-(1H-Tetrazol-5-yl)-4(3H)-quinazolinones THE DOW CHEMICAL COMPANY (US) 1983-12-06 US disclosed
EP-0086340-A1 3-(1H-tetrazol-5-yl)-4(3H)-quinazolinones THE DOW CHEMICAL COMPANY (US) 1983-08-24 EP disclosed
EP-0045423-A1 Process for the alpha-halogenation of possibly substituted methyl aromatics BAYER AG (DE) 1982-02-10 EP disclosed
US-4046805-A Substituted-hydroxy-naphthalenedisulfonic acid compounds AMERICAN CYANAMID COMPANY (US) 1977-09-06 US disclosed
US-3971741-A DISPERSION PIGMENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250042932-A1 METHOD FOR PRODUCING POLYNUCLEOTIDES POLN, RNGTT, PNP TSHR 3858/4885CYP3A4 2487/4885MAPT 2128/4885
US-20250215040-A1 METHOD AND COMPOUND POLN, POLRMT, FBL TSHR 1888/4885CYP3A4 4230/4885MAPT 3064/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.