Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5532405 | 0.81 | ALDH1A1 (0.54) | NTRK1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL29002505 | 0.79 | KDM4E (0.53) | NTRK1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL4917844 | 0.79 | NTRK1 (0.45) | NTRK1SYKAURKBINCENPALDH1A1 | |
| SCHEMBL20124614 | 0.75 | ALDH1A1 (0.49) | NTRK1SYKAURKBINCENPTDP1 | |
| SCHEMBL11733981 | 0.74 | PDE10A (0.52) | NTRK1SYKAURKBINCENPTDP1 | |
| SCHEMBL5360517 | 0.72 | SYK (0.45) | NTRK1SYKAURKBINCENPTDP1 | |
| SCHEMBL15716526 | 0.71 | ADORA2A (0.49) | SYKAURKBINCENPTDP1ALDH1A1 | |
| SCHEMBL30573063 | 0.71 | ADORA1 (0.49) | NTRK1SYKAURKBINCENPTDP1 | |
| SCHEMBL26606982 | 0.71 | ADORA1 (0.49) | NTRK1SYKAURKBINCENPTDP1 | |
| SCHEMBL28329598 | 0.70 | ALDH1A1 (0.41) | TDP1ALDH1A1KDM4ESMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885817-B1 | RESPONSIVE LUMINESCENT LANTHANIDE COMPLEXES | UNIV DURHAM (GB) | 2016-05-11 | — | — | EP | disclosed |
| US-8193174-B2 | Responsive luminescent lanthanide complexes | UNIVERSITY OF DURHAM (GB) | 2012-06-05 | — | — | US | disclosed |
| US-20080312431-A1 | Responsive Luminescent Lanthanide Complexes | UNIVERSITY OF DURHAM (GB) | 2008-12-18 | — | — | US | disclosed |
| EP-1885817-A1 | RESPONSIVE LUMINESCENT LANTHANIDE COMPLEXES | UNIVERSITY OF DURHAM (GB) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006120444-A1 | RESPONSIVE LUMINESCENT LANTHANIDE COMPLEXES | UNIVERSITY OF DURHAM (GB) | 2006-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312431-A1 | Responsive Luminescent Lanthanide Complexes | TPR, NLRP1, NISCH | NTRK1 171/4885SYK 3553/4885AURKB 2391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.