⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579105 | 1.00 | — | — | |
| SCHEMBL6577101 | 1.00 | — | — | |
| SCHEMBL27789715 | 0.77 | — | — | |
| SCHEMBL108561 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL1515897 | 0.74 | — | — | |
| SCHEMBL10778756 | 0.74 | — | — | |
| E968 SCHEMBL17062 | 0.74 | — | — | |
| E968 SCHEMBL6729753 | 0.74 | — | — | |
| E968 SCHEMBL2723809 | 0.74 | LMNA (0.67) | — | |
| E968 SCHEMBL10427336 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150008159-A1 | SEPARATION OF SELECTED ASPHALTENES FROM A HYDROCARBON-CONTAINING FEEDSTOCK | SHELL OIL COMPANY | 2015-01-08 | — | — | US | disclosed |
| WO-2015002868-A1 | SEPARATION OF SELECTED ASPHALTENES FROM A HYDROCARBON-CONTAINING FEEDSTOCK | SHELL OIL COMPANY (US) | 2015-01-08 | — | — | WO | disclosed |
| US-8492560-B2 | Quinazoline derivatives as angiogenesis inhibitors | ASTRAZENECA AB (SE) | 2013-07-23 | — | — | US | disclosed |
| US-20120197027-A1 | Quinazoline Derivatives as Angiogenesis Inhibitors | STOKES ELAINE S E (GB) | 2012-08-02 | — | — | US | disclosed |
| US-8106073-B2 | Quinoline derivatives 057 | ASTRAZENECA AB (SE) | 2012-01-31 | — | — | US | disclosed |
| EP-1633717-B1 | P2X7 RECEPTOR ANTAGONISTS AND THEIR USE | ASTRAZENECA AB (SE) | 2009-10-28 | — | — | EP | disclosed |
| US-20090143428-A1 | Quinoline Derivatives 057 | ASTRAZENECA AB (SE) | 2009-06-04 | — | — | US | disclosed |
| US-20090143354-A1 | P2X7 Receptor Antagonists and Their Use | ASTRAZENECA AB (SE) | 2009-06-04 | — | — | US | disclosed |
| EP-2050744-A1 | Quinazoline derivatives as angiogenesis inhibitors | AstraZeneca AB (SE) | 2009-04-22 | — | — | EP | disclosed |
| US-7408065-B2 | P2X7 receptor antagonists and their use | ASTRAZENECA AB (SE) | 2008-08-05 | — | — | US | disclosed |
| EP-1154774-B1 | QUINAZOLINE DERIVATIVES AS ANGIOGENESIS INHIBITORS | ASTRAZENECA AB (SE) | 2005-06-22 | — | — | EP | disclosed |
| WO-2004106305-A1 | NEW P2X7 RECEPTOR ANTAGONISTS AND THEIR USE | ASTRAZENECA AB (SE) | 2004-12-09 | — | — | WO | disclosed |
| US-20040214881-A1 | Method for producing optically active halopropanediol derivative | KANEKA CORPORATION (JP) | 2004-10-28 | — | — | US | disclosed |
| EP-1422213-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE HALOPROPANEDIOL DERIVATIVE | KANEKA CORPORATION (JP) | 2004-05-26 | — | — | EP | disclosed |
| EP-1154774-A1 | QUINAZOLINE DERIVATIVES AS ANGIOGENESIS INHIBITORS | AstraZeneca AB (SE) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000047212-A1 | QUINAZOLINE DERIVATIVES AS ANGIOGENESIS INHIBITORS | ASTRAZENECA AB (SE) | 2000-08-17 | — | — | WO | disclosed |
| US-4302272-A | HEATING SURFACE OF A POLYETHERURETHANE ABOVE ITS MELTING POINT FOLLOWED BY COOLING | MOBAY CHEMICAL CORPORATION (US) | 1981-11-24 | — | — | US | disclosed |
| US-4282332-A | POLYURETHANES | MOBAY CHEMICAL CORPORATION (US) | 1981-08-04 | — | — | US | disclosed |
| US-4234745-A | Polyols derived from 4,4,4-trichloro-1,2-epoxybutane and/or epihalohydrin for use in the production of heat sealable foams | MOBAY CHEMICAL CORPORATION (US) | 1980-11-18 | — | — | US | disclosed |
| US-4064309-A | Process for printing fibrous material | BASF AKTIENGESELLSCHAFT (DT) | 1977-12-20 | — | — | US | disclosed |