Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acridine SCHEMBL4972293 | 0.72 | ALDH1A1 (1.00) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL1772714 | 0.72 | ALDH1A1 (1.00) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL3045498 | 0.72 | ALDH1A1 (1.00) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL8339 | 0.72 | ALDH1A1 (1.00) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL29352289 | 0.72 | ALDH1A1 (1.00) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL641951 | 0.69 | ALDH1A1 (0.94) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL1551975 | 0.69 | ALDH1A1 (0.94) | ALDH1A1HPGDGLAMAPTACHE | |
| Acridine SCHEMBL10801271 | 0.69 | ALDH1A1 (0.94) | ALDH1A1HPGDGLAMAPTACHE | |
| Anthracene SCHEMBL9879830 | 0.69 | MAPT (0.94) | ALDH1A1HPGDGLAMAPTACHE | |
| SCHEMBL5469928 | 0.69 | MAPT (0.82) | ALDH1A1HPGDGLAMAPTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551862-B | Macrocyclic inhibitors of peptidyl arginine deiminase | 吉利德科学公司 | 2024-04-12 | — | — | CN | disclosed |
| WO-2023116804-A1 | LIPID COMPOUND AND LIPID NANOPARTICLE COMPOSITION | 苏州艾博生物科技有限公司 | 2023-06-29 | — | — | WO | disclosed |
| CN-108623619-B | Process for preparing C-Met tyrosine kinase inhibitors | 江苏豪森药业集团有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-113412542-A | Color-tunable LED-OLED hybrid guided lighting device | 李坚 | 2021-09-17 | — | — | CN | disclosed |
| CN-109053699-A | A kind of preparation method of cycolxylidin | 四川和邦生物科技股份有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-105481839-B | A kind of preparation method of photolytic activity epoxy quinoline enantiomer | 安徽千和新材料科技发展有限公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-105367557-B | A kind of preparation method of epoxy quinoline | 安徽千和新材料科技发展有限公司 | 2018-04-24 | — | — | CN | disclosed |
| CN-107735880-A | Efficient O L ED device with extremely short decay time | UDC 爱尔兰有限责任公司 | 2018-02-23 | — | — | CN | disclosed |
| CN-105481839-A | Preparation method for cycloxylidin enantiomer with photoactivity | ANHUI QIANHE NEW MAT SCIENCE & TECH DEV CO LTD | 2016-04-13 | — | — | CN | disclosed |
| CN-105367557-A | Method for preparing cycloxylidin | ANHUI QIANHE NEW MAT SCIENCE & TECH DEV CO LTD | 2016-03-02 | — | — | CN | disclosed |
| US-20080312185-A1 | SUBSTITUTED 3-AMINO-THIENO[2,3-b]PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS AND PROCESSES FOR PREPARING AND THEIR USES | CHEN ZHIDONG | 2008-12-18 | — | — | US | disclosed |
| US-20060270671-A1 | Substituted 3-amino-thieno[2,3-b] pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-11-30 | — | — | US | disclosed |
| US-7119102-B2 | Substituted 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-10-10 | — | — | US | disclosed |
| EP-1692141-A1 | SUBSTITUTED 3-AMINO-THIENO¬2,3-B| PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS AS IKK INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2006-08-23 | — | — | EP | disclosed |
| US-20050182053-A1 | Substituted 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-08-18 | — | — | US | disclosed |
| WO-2005056562-A1 | SUBSTITUTED 3-AMINO-THIENO[2,3-B] PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS AS IKK INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182053-A1 | Substituted 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses | NFKBIA, IKBKG, IKBKE | ALDH1A1 3655/4885HPGD 2067/4885GLA 3410/4885 |
| US-20060270671-A1 | Substituted 3-amino-thieno[2,3-b] pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses | CPS1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TK2 | ALDH1A1 371/4885HPGD 869/4885GLA 1173/4885 |
| US-20080312185-A1 | SUBSTITUTED 3-AMINO-THIENO[2,3-b]PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS AND PROCESSES FOR PREPARING AND THEIR USES | CPS1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TK2 | ALDH1A1 371/4885HPGD 869/4885GLA 1173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.