Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29560364 | 0.79 | TSHR (0.37) | TSHRKDM4EALDH1A1MAPT | |
| SCHEMBL2955010 | 0.79 | TSHR (0.37) | TSHRKDM4EALDH1A1MAPT | |
| SCHEMBL17316478 | 0.72 | TSHR (0.39) | TSHRVCAM1KDM4EALDH1A1MAPT | |
| SCHEMBL7844027 | 0.65 | DYRK1A (0.34) | GSRTSHRKDM4EALDH1A1MAPT | |
| SCHEMBL11293059 | 0.64 | TSHR (0.39) | TSHRKDM4EALDH1A1MAPT | |
| SCHEMBL10552293 | 0.63 | TSHR (0.33) | TSHRKDM4EALDH1A1 | |
| SCHEMBL11956555 | 0.63 | KDM4E (0.38) | GPR84TSHRKDM4EALDH1A1MAPT | |
| SCHEMBL8270010 | 0.63 | HDAC8 (0.42) | TSHRALDH1A1 | |
| SCHEMBL11689845 | 0.61 | TSHR (0.40) | TSHRKDM4EALDH1A1MAPT | |
| SCHEMBL1348478 | 0.60 | ALDH1A1 (0.32) | GPR84KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176906-A1 | Substituted Pyrrole Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-07-24 | — | — | US | disclosed |
| EP-1824841-A1 | SUBSTITUTED PYRROLE DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006064944-A1 | SUBSTITUTED PYRROLE DERIVATIVE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176906-A1 | Substituted Pyrrole Derivative | AR, NR5A1, MC2R | GPR84 265/4885GSR 1759/4885TSHR 165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.