Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4919757 | 0.88 | PTGS1 (0.41) | PTGS1PTGS2TP53CA2SIRT1 | |
| SCHEMBL4914436 | 0.87 | PTGS1 (0.39) | PTGS1PTGS2CA2SIRT1SIRT2 | |
| SCHEMBL27817405 | 0.77 | TP53 (0.34) | TP53SIRT1LMNA | |
| SCHEMBL2582217 | 0.75 | PTGS1 (0.39) | PTGS1PTGS2CA2 | |
| SCHEMBL1963457 | 0.73 | PTGS1 (0.42) | PTGS1PTGS2CA2LMNAAGTR2 | |
| SCHEMBL1964543 | 0.72 | PTGS1 (0.40) | PTGS1PTGS2TP53CA2LMNA | |
| SCHEMBL514838 | 0.72 | PTGS1 (0.38) | PTGS1PTGS2CA2SIRT1 | |
| SCHEMBL2581430 | 0.72 | FADS1 (0.39) | PTGS1PTGS2CA2 | |
| SCHEMBL27815096 | 0.71 | MEN1 (0.43) | PTGS1PTGS2CA2LMNAALDH1A1 | |
| SCHEMBL513997 | 0.71 | PTGS1 (0.39) | PTGS1PTGS2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080274892-A1 | Novel Haloalkylsulfonanilide Derivative, Herbicide, and Method of Use Thereof | NIHON NOHYAKU CO., LTD. (JP) | 2008-11-06 | — | — | US | disclosed |
| EP-1852425-A1 | NOVEL HALOALKYLSULFONANILIDE DERIVATIVE, HERBICIDE, AND METHOD OF USE THEREOF | Nihon Nohyaku Co., Ltd. (JP) | 2007-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274892-A1 | Novel Haloalkylsulfonanilide Derivative, Herbicide, and Method of Use Thereof | HDHD5, DDT, CBR3 | PTGS1 3550/4885PTGS2 3734/4885TP53 3986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.