Ether

Ether

SCHEMBL4920147

CC(F)=C(F)F.CCOCC

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
TSHR P16473 1/20 0.36
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrafluoroethylene SCHEMBL4488709 0.86 ALDH1A1 (0.42) ALDH1A1TSHR
Ether SCHEMBL9147587 0.80 ALDH1A1 (0.38) ALDH1A1TSHR
Tetrafluoroethylene SCHEMBL5137043 0.78 ALDH1A1 (0.50) ALDH1A1TSHR
Ether SCHEMBL27094820 0.76
Ether SCHEMBL21437079 0.74 ALDH1A1 (0.44) ALDH1A1TSHRLMNAHSD17B10THRB
Ether SCHEMBL8349382 0.73 ALDH1A1 (0.50) ALDH1A1TSHRLMNAHSD17B10THRB
Ether SCHEMBL7435965 0.73 ALDH1A1 (0.50) ALDH1A1TSHRLMNAHSD17B10THRB
Ether SCHEMBL135123 0.73
Ether SCHEMBL1766202 0.73
Ether SCHEMBL27348478 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10597346-B2 Methods for producing solvents derived from 1-chloro-3, 3, 3-trifluoro-propene (1233zd) HONEYWELL INTERNATIONAL INC. (US) 2020-03-24 US disclosed
US-20190292120-A1 METHODS FOR PRODUCING SOLVENTS DERIVED FROM 1-CHLORO-3, 3, 3-TRIFLUORO-PROPENE (1233ZD) SOLSTICE ADVANCED MATERIALS US, INC. 2019-09-26 US disclosed
US-10351499-B2 Methods for producing solvents derived from 1-chloro-3, 3, 3-trifluoro-propene (1233zd) HONEYWELL INTERNATIONAL INC. (US) 2019-07-16 US disclosed
EP-3464227-A1 METHODS FOR PRODUCING SOLVENTS DERIVED FROM 1-CHLORO-3, 3, 3-TRIFLUORO-PROPENE (1233ZD) Honeywell International Inc. (US) 2019-04-10 EP disclosed
WO-2017210165-A1 METHODS FOR PRODUCING SOLVENTS DERIVED FROM 1-CHLORO-3, 3, 3-TRIFLUORO-PROPENE (1233ZD) HONEYWELL INTERNATIONAL INC. (US) 2017-12-07 WO disclosed
US-20170349519-A1 METHODS FOR PRODUCING SOLVENTS DERIVED FROM 1-CHLORO-3, 3, 3-TRIFLUORO-PROPENE (1233ZD) SOLSTICE ADVANCED MATERIALS US, INC. 2017-12-07 US disclosed
US-20080003688-A1 Method for Measuring the Acidity of Hydrocarbons TOTAL FRANCE (FR) 2008-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170349519-A1 METHODS FOR PRODUCING SOLVENTS DERIVED FROM 1-CHLORO-3, 3, 3-TRIFLUORO-PROPENE (1233ZD) JUND, TUBA3C, DRD3 ALDH1A1 739/4885TSHR 725/4885LMNA 4316/4885
US-20190292120-A1 METHODS FOR PRODUCING SOLVENTS DERIVED FROM 1-CHLORO-3, 3, 3-TRIFLUORO-PROPENE (1233ZD) JUND, TUBA3C, DRD3 ALDH1A1 739/4885TSHR 725/4885LMNA 4316/4885
US-10597346-B2 Methods for producing solvents derived from 1-chloro-3, 3, 3-trifluoro-propene (1233zd) JUND, TUBA3C, DRD3 ALDH1A1 739/4885TSHR 725/4885LMNA 4316/4885
US-10351499-B2 Methods for producing solvents derived from 1-chloro-3, 3, 3-trifluoro-propene (1233zd) JUND, TUBA3C, DRD3 ALDH1A1 739/4885TSHR 725/4885LMNA 4316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.