SCHEMBL4921371

SCHEMBL4921371

Cc1ccccc1S(=O)(=O)[O-].c1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 0.41
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
SLC1A1 P43005 1/20 0.34
POLB P06746 1/20 0.34
SFRP1 Q8N474 1/20 0.34
PTGES2 Q9H7Z7 1/20 0.33
HIF1A Q16665 1/20 0.33
ITGAV P06756 1/20 0.33
RAPGEF4 Q8WZA2 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7064046 0.90 SNCA (0.39) SNCAPOLBKMT2A
SCHEMBL6230991 0.84 RAPGEF4 (0.38) SLC1A3SLC1A2SLC1A1HIF1AITGAV
SCHEMBL4922529 0.82 SNCA (0.50) SNCAPOLBHIF1A
SCHEMBL4921374 0.80 CYP3A4 (0.46) SNCAKMT2A
SCHEMBL6232586 0.78 HIF1A (0.38) SLC1A3SLC1A2SLC1A1HIF1AITGAV
SCHEMBL4463635 0.76 MEN1 (0.42) SLC1A3SLC1A2SLC1A1POLBRAPGEF4
SCHEMBL57931 0.76 TDP1 (0.45) RAPGEF4KMT2A
SCHEMBL5399285 0.76 HSD11B1 (0.42) RAPGEF4KMT2A
SCHEMBL6915057 0.76 HSD11B1 (0.42) RAPGEF4KMT2A
SCHEMBL20658918 0.76 HSD11B1 (0.42) RAPGEF4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080032080-A1 Thermoplastic, moldable polymer composition and dynamic vulcanizates thereof DAIKIN AMERICA, INC. (US) 2008-02-07 US disclosed
US-4145473-A Antistatic filament having a polymeric sheath and a conductive polymeric core E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-03-20 US disclosed