Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2475489 | 0.84 | TAAR1 (0.53) | ALDH1A1LMNAKDM4E | |
| SCHEMBL14025455 | 0.82 | ALDH1A1 (0.51) | ALDH1A1LMNAKMT2AMEN1CXCR4 | |
| SCHEMBL4921625 | 0.79 | NAMPT (0.49) | ALDH1A1LMNAKMT2AMEN1CXCR4 | |
| SCHEMBL14025461 | 0.76 | CXCR3 (0.47) | ALDH1A1LMNAKMT2AMEN1CXCR4 | |
| SCHEMBL14025460 | 0.76 | NAMPT (0.52) | ALDH1A1LMNAKMT2AMEN1CXCR4 | |
| SCHEMBL407669 | 0.75 | ALDH1A1 (0.73) | ALDH1A1LMNAKMT2AMEN1CXCR4 | |
| SCHEMBL14025459 | 0.74 | ALDH1A1 (0.45) | ALDH1A1LMNAKMT2AMEN1CXCR4 | |
| SCHEMBL9373823 | 0.73 | ALDH1A1 (0.66) | ALDH1A1LMNAKMT2AMEN1CXCR4 | |
| SCHEMBL4926285 | 0.72 | CXCR3 (0.56) | ALDH1A1LMNAKMT2AMEN1CXCR4 | |
| SCHEMBL14470257 | 0.72 | ALDH1A1 (0.69) | ALDH1A1LMNAKMT2AMEN1CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080261978-A1 | treating or preventing HIV infections, and in treating proliferative disorders such as inhibiting the metastasis of various cancers; 1-(4-((pyridin-2-ylmethylamino)methyl)benzyl)-3-phenylurea | METASTATIX, INC. | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261978-A1 | treating or preventing HIV infections, and in treating proliferative disorders such as inhibiting the metastasis of various cancers; 1-(4-((pyridin-2-ylmethylamino)methyl)benzyl)-3-phenylurea | MKI67, CCNI, CDKN1A | ALDH1A1 423/4885LMNA 2811/4885KMT2A 682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.