Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4911102 | 0.90 | MAPT (0.59) | MAPTMEN1KMT2ATRPV1CASP3 | |
| SCHEMBL4063794 | 0.84 | TLR2 (0.54) | MAPTMEN1KMT2ATRPV1CASP3 | |
| SCHEMBL4922844 | 0.81 | MAPT (0.75) | MAPTMEN1KMT2ATRPV1CASP3 | |
| SCHEMBL1019967 | 0.79 | SMN1; SMN2 (0.78) | MAPTMEN1KMT2ATRPV1CASP3 | |
| SCHEMBL10470287 | 0.79 | ABCC1 (0.58) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4113307 | 0.77 | MAPT (0.77) | MAPTMEN1KMT2ATRPV1CASP3 | |
| SCHEMBL13891557 | 0.77 | PTPN2 (0.60) | MAPTKMT2ACASP3SENP7SMN1; SMN2 | |
| SCHEMBL29072086 | 0.77 | MAPT (0.60) | MAPTMEN1KMT2ATRPV1CASP3 | |
| SCHEMBL31238157 | 0.77 | SMN1; SMN2 (0.63) | MAPTMEN1KMT2ATRPV1CASP3 | |
| SCHEMBL4915127 | 0.76 | MAPT (0.75) | MAPTMEN1KMT2ATRPV1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080261952-A1 | Aryl Urea Derivatives for Treating Obesity | PROSIDION LTD. (GB) | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261952-A1 | Aryl Urea Derivatives for Treating Obesity | CNR1, GPR119, UTS2R | MAPT 4151/4885MEN1 4843/4885KMT2A 1905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.