Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612259 | 0.74 | RARB (0.32) | TRPA1 | |
| SCHEMBL16052925 | 0.72 | — | — | |
| SCHEMBL11824227 | 0.69 | MEN1 (0.30) | — | |
| SCHEMBL10362031 | 0.68 | HIF1A (0.30) | — | |
| SCHEMBL3259380 | 0.68 | — | — | |
| SCHEMBL8609976 | 0.67 | — | — | |
| SCHEMBL13517879 | 0.64 | NAMPT (0.31) | — | |
| SCHEMBL8634137 | 0.64 | — | — | |
| SCHEMBL9493642 | 0.63 | — | — | |
| SCHEMBL11467322 | 0.61 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214419-A1 | Naphthalenone Derivative with Powdery-Ionone Type Odors | FIRMENICH SA (CH) | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214419-A1 | Naphthalenone Derivative with Powdery-Ionone Type Odors | IPO5, TRPA1, SCN5A | TRPA1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.