Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.46 |
| ▸ | MEF2D | Q14814 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4933486 | 0.90 | HDAC2 (0.50) | ALDH1A1SMN1; SMN2HDAC4HDAC1HDAC3 | |
| SCHEMBL4922692 | 0.90 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2HDAC4HDAC1HDAC3 | |
| SCHEMBL4922546 | 0.89 | LMNA (0.47) | ALDH1A1SMN1; SMN2HDAC4HDAC1HDAC3 | |
| SCHEMBL4933386 | 0.87 | HDAC8 (0.47) | ALDH1A1SMN1; SMN2HDAC4HDAC1HDAC3 | |
| SCHEMBL4923053 | 0.86 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2HDAC4HDAC1HDAC3 | |
| SCHEMBL4930697 | 0.85 | HDAC1 (0.52) | ALDH1A1SMN1; SMN2HDAC4HDAC1HDAC3 | |
| SCHEMBL4922683 | 0.85 | HDAC3 (0.49) | ALDH1A1SMN1; SMN2HDAC4HDAC1HDAC3 | |
| SCHEMBL4930165 | 0.85 | HDAC2 (0.52) | ALDH1A1SMN1; SMN2HDAC4HDAC1HDAC3 | |
| SCHEMBL4931762 | 0.84 | HDAC1 (0.51) | ALDH1A1SMN1; SMN2HDAC4HDAC1HDAC3 | |
| SCHEMBL4931121 | 0.84 | HDAC3 (0.46) | ALDH1A1SMN1; SMN2HDAC4HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | S*BIO PTE LTD. (SG) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | HDAC1, HDAC3, HDAC4 | ALDH1A1 1020/4885SMN1; SMN2 2353/4885HDAC4 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.