Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | IGLV6-57 | P01721 | 9/20 | 0.45 |
| ▸ | ATM | Q13315 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 3/20 | 0.43 |
| ▸ | CASP7 | P55210 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4926559 | 0.88 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTHPGDL3MBTL1 | |
| SCHEMBL16316729 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTHPGDL3MBTL1 | |
| SCHEMBL24590073 | 0.81 | IGLV6-57 (0.61) | ALDH1A1KDM4EMAPTHPGDL3MBTL1 | |
| SCHEMBL4929175 | 0.73 | EP300 (0.56) | ALDH1A1KDM4EMAPTHPGDL3MBTL1 | |
| SCHEMBL4927809 | 0.73 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTHPGDL3MBTL1 | |
| SCHEMBL13869309 | 0.72 | ALDH1A1 (0.86) | ALDH1A1KDM4EMAPTHPGDL3MBTL1 | |
| SCHEMBL29249873 | 0.72 | ALDH1A1 (0.69) | ALDH1A1KDM4EMAPTHPGDL3MBTL1 | |
| SCHEMBL22501670 | 0.72 | IGLV6-57 (0.65) | ALDH1A1KDM4EMAPTHPGDL3MBTL1 | |
| SCHEMBL30914647 | 0.72 | ALDH1A1 (0.69) | ALDH1A1KDM4EMAPTHPGDL3MBTL1 | |
| SCHEMBL26978514 | 0.72 | ALDH1A1 (0.69) | ALDH1A1KDM4EMAPTHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE | 2008-08-14 | — | — | US | disclosed |
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE | 2008-08-14 | — | — | US | disclosed |
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | MAOA, MAOB, COMT | ALDH1A1 181/4885KDM4E 1183/4885MAPT 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.