SCHEMBL492248

SCHEMBL492248

C=CCOC(=O)OOOC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
CYP3A4 P08684 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
MAPT P10636 1/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6565508 0.89 TSHR (0.38) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL28267237 0.87 TSHR (0.37) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL9752370 0.86 TSHR (0.34) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL10435386 0.85 ALDH1A1 (0.34) TSHRTDP1ALDH1A1HSD17B10
SCHEMBL9752493 0.84 ALDH1A1 (0.30) ALDH1A1
SCHEMBL28572466 0.84
SCHEMBL10911224 0.83 TSHR (0.33) TSHRCYP3A4TDP1
SCHEMBL10939915 0.83 TDP1 (0.36) TSHRCYP3A4TDP1SMN1; SMN2
SCHEMBL22164087 0.82 TSHR (0.34) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL29876466 0.82 CYP3A4 (0.42) TSHRCYP3A4TDP1MAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 413 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050277061-A1 Polymeric material for laser processing and a laminated body for laser processing thereof, flexographic printing plate and the method of producing the same, and a seal material JSR CORPORATION (JP) 2005-12-15 US claimed
EP-0798319-B1 Elastic fluorohydrocarbon resin and method of producing same CENTRAL GLASS CO LTD (JP) 2000-11-02 EP claimed
EP-0523644-B1 Plastic laminate having polyamide resin surface layer and fluororesin surface layer CENTRAL GLASS CO LTD (JP) 1997-11-12 EP claimed
US-5569716-A COMPRISING A HYDROCARBON RUBBER, A VULCANIZING OR CROSSLINKING AGENT AND A HYDROGENATED PETROLEUM RESIN IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1996-10-29 US claimed
EP-0520729-B1 Urethane elastomer based thermoplastic resin composition suitable for extrusion CENTRAL GLASS CO LTD (JP) 1996-03-20 EP claimed
EP-0295821-B1 Method for production of graft resin composition NIPPON OILS & FATS CO LTD (JP) 1994-01-05 EP claimed
US-5185405-A High molecular weight vinyl arene/acrylic ester copolymer polymerized using a diperoxy catalyst blended with a low molecular weight styrene/acrylic ester polymer; low fixing temperature; offset resistance SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1993-02-09 US claimed
WO-1991000301-A1 (CO)POLYMER MODIFICATION EMPLOYING UNSATURATED t-ALKYL PEROXYALKENYL CARBONATES AKZO N.V. (NL) 1991-01-10 WO claimed
US-4590248-A POLYMERIZATION OF BIS(ALLYL CARBONATE)OF DIETHYLENE GLYCOL NIPPON OIL AND FATS CO., LTD. (JP) 1986-05-20 US claimed
US-4533699-A WITH VINYL ACETATE MONOMER AND CUPLING AGENT NIPPON OIL & FATS CO., LTD. (JP) 1985-08-06 US claimed
US-4366290-A UNSATURATED PEROXYCARBONATE NIPPON OIL AND FATS CO., LTD. (JP) 1982-12-28 US claimed
US-4119657-A COMONOMERS WITH NON-CONJUGATED ETHENICALLY UNSATURATED COMPOUNDS NIHON OIL AND FATS CO., LTD. (JP) 1978-10-10 US claimed
JP-55118927-A None JP disclosed
JP-61203109-A None JP disclosed
JP-56139514-A None JP disclosed
JP-61111314-A None JP disclosed
JP-S55118927-A PRODUCTION OF CROSSLINKED VINYL CHLORIDE RESIN TOAGOSEI CHEM IND CO LTD 1980-09-12 JP disclosed
US-4119657-A COMONOMERS WITH NON-CONJUGATED ETHENICALLY UNSATURATED COMPOUNDS NIHON OIL AND FATS CO., LTD. (JP) 1978-10-10 US disclosed
JP-S52153916-A NOVEL PEROXYCARBONATE NIPPON OIL & FATS CO LTD 1977-12-21 JP disclosed
US-4061704-A Tertiary-alkylperoxy alkyl carbonate initiators for hot air vulcanization of silicone rubber PPG INDUSTRIES, INC. (US) 1977-12-06 US disclosed