Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076124 | 0.92 | TSHR (0.38) | TSHRCYP3A4 | |
| SCHEMBL10911224 | 0.87 | TSHR (0.33) | TSHRCYP3A4TDP1 | |
| SCHEMBL11298530 | 0.87 | TSHR (0.48) | TSHRCYP3A4MAPT | |
| SCHEMBL492248 | 0.86 | TSHR (0.36) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL9752447 | 0.85 | — | — | |
| SCHEMBL10939915 | 0.80 | TDP1 (0.36) | TSHRCYP3A4TDP1 | |
| SCHEMBL29876466 | 0.79 | CYP3A4 (0.42) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL6565508 | 0.78 | TSHR (0.38) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL11517813 | 0.78 | TSHR (0.47) | TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL7930937 | 0.77 | TSHR (0.35) | TSHRCYP3A4TDP1MAPTCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991000301-A1 | (CO)POLYMER MODIFICATION EMPLOYING UNSATURATED t-ALKYL PEROXYALKENYL CARBONATES | AKZO N.V. (NL) | 1991-01-10 | — | — | WO | claimed |
| WO-1991000301-A1 | (CO)POLYMER MODIFICATION EMPLOYING UNSATURATED t-ALKYL PEROXYALKENYL CARBONATES | AKZO N.V. (NL) | 1991-01-10 | — | — | WO | disclosed |