Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | USP5 | P45974 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28288945 | 0.80 | HDAC3 (0.47) | MAPK1CYP2D6HIF1AEGFRHCAR2 | |
| SCHEMBL4925193 | 0.79 | MEN1 (0.42) | MAPK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL153243 | 0.75 | TYR (0.52) | KDM4EMAPK1CYP2C9CYP2D6HIF1A | |
| SCHEMBL13278918 | 0.72 | HSD17B10 (0.50) | KDM4EMAPK1CYP2C9HIF1ASMN1; SMN2 | |
| SCHEMBL13278916 | 0.72 | HSD17B10 (0.50) | KDM4EMAPK1CYP2C9HIF1ASMN1; SMN2 | |
| SCHEMBL10169451 | 0.72 | CYP2C9 (0.66) | KDM4EMAPK1CYP2C9CYP2D6HIF1A | |
| Hydrogen Peroxide SCHEMBL28795529 | 0.71 | CYP2C9 (0.57) | KDM4EMAPK1CYP2C9CYP2D6HIF1A | |
| Hydrogen Peroxide SCHEMBL2387288 | 0.71 | CYP2C9 (0.57) | KDM4EMAPK1CYP2C9CYP2D6HIF1A | |
| SCHEMBL10426785 | 0.71 | CYP2C9 (0.69) | KDM4EMAPK1CYP2C9CYP2D6HIF1A | |
| SCHEMBL819055 | 0.71 | KDM4E (1.00) | KDM4EMAPK1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021087-A1 | Cannabinoid receptor modulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2008-01-24 | — | — | US | disclosed |
| EP-1637527-A1 | CANNABINOID RECEPTOR MODULATOR | Takeda Pharmaceutical Company Limited (JP) | 2006-03-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021087-A1 | Cannabinoid receptor modulator | CNR1, CNR2, GPR18 | KDM4E 737/4885MAPK1 1115/4885CYP2C9 184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.