Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 16/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4921595 | 0.88 | PTGES (0.43) | PTGESPPARGPPARANR1H4 | |
| SCHEMBL4926075 | 0.83 | PTGES (0.54) | PTGESPPARGPPARA | |
| SCHEMBL334827 | 0.76 | PTGES (0.55) | PTGESPPARGPPARA | |
| SCHEMBL4228390 | 0.74 | PPARG (0.50) | PTGESPPARGPPARA | |
| SCHEMBL4027503 | 0.72 | PTGES (0.71) | PTGESPPARGPPARA | |
| SCHEMBL4914794 | 0.72 | PTGES (0.46) | PTGESPPARGPPARANR1H4 | |
| SCHEMBL4925712 | 0.71 | PTGES (0.81) | PTGESPPARGPPARANR1H4 | |
| SCHEMBL335009 | 0.71 | PTGES (0.52) | PTGESPPARGPPARA | |
| SCHEMBL3014883 | 0.71 | PPARG (0.50) | PTGESPPARGPPARA | |
| SCHEMBL3013326 | 0.70 | PTGES (0.62) | PTGESPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249091-A1 | Indoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249091-A1 | Indoles Useful in the Treatment of Inflammation | IDO1, IDO2, ARG1 | PTGES 35/4885PPARG 2586/4885PPARA 3339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.