SCHEMBL4923137

SCHEMBL4923137

CCCCCOC(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 1/20 0.45
LTA4H P09960 1/20 0.44
DNM1 Q05193 1/20 0.44
CTSK P43235 3/20 0.43
CETP P11597 3/20 0.41
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
SIGMAR1 Q99720 2/20 0.41
ALDH1A1 P00352 1/20 0.40
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
PLA2G10 O15496 1/20 0.40
PLA2G2A P14555 1/20 0.40
TLR2 O60603 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6251205 0.91 CSNK1E (0.45) CSNK1ELTA4HDNM1CTSKCETP
SCHEMBL13725562 0.89 CSNK1E (0.43) CSNK1ELTA4HDNM1CTSKCETP
SCHEMBL3270666 0.87 CSNK1E (0.46) CSNK1ELTA4HDNM1CETPSIGMAR1
SCHEMBL7924701 0.86 ALDH1A1 (0.41) CSNK1ELTA4HCTSKCTSLCTSB
SCHEMBL8080331 0.82 CSNK1E (0.43) CSNK1ELTA4HDNM1CETPSIGMAR1
SCHEMBL28475117 0.82 CSNK1E (0.50) CSNK1ELTA4HCETPSIGMAR1
SCHEMBL3275777 0.81 LTA4H (0.46) CSNK1ELTA4HSIGMAR1ALDH1A1
SCHEMBL8084672 0.81 CSNK1E (0.45) CSNK1ELTA4HDNM1CETPALDH1A1
SCHEMBL8080276 0.81 CSNK1E (0.45) CSNK1ELTA4HDNM1CETPALDH1A1
SCHEMBL16020623 0.81 CSNK1E (0.45) CSNK1ELTA4HDNM1CETPALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080057138-A1 RESTORATIVE SKIN CREAM TELFORD HOLDINGS LTD. (CA) 2008-03-06 US claimed
US-6994844-B2 Photostable UV-screening compositions comprising dibenzoylmethane/diarylbutadiene compounds L'OREAL (FR) 2006-02-07 US disclosed
US-5118707-A Compositions for regulating skin wrinkles comprising a benzofuran derivative THE PROCTER & GAMBLE COMPANY (US) 1992-06-02 US disclosed