Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 6/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30473687 | 0.79 | BACE1 (0.50) | SMN1; SMN2DYRK1AHTTNPSR1ALDH1A1 | |
| SCHEMBL4819657 | 0.79 | BACE1 (0.50) | SMN1; SMN2DYRK1AHTTNPSR1ALDH1A1 | |
| SCHEMBL31752133 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2DYRK1AHTTNPSR1ALDH1A1 | |
| SCHEMBL29862595 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2DYRK1AHTTNPSR1ALDH1A1 | |
| SCHEMBL12687394 | 0.79 | DYRK1B (0.38) | SMN1; SMN2DYRK1AHTTNPSR1ALDH1A1 | |
| SCHEMBL23360456 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2DYRK1AHTTNPSR1ALDH1A1 | |
| SCHEMBL21114788 | 0.79 | NOS1 (0.37) | SMN1; SMN2DYRK1AHTTMAPK1CYP2A6 | |
| SCHEMBL13226821 | 0.76 | SMN1; SMN2 (0.40) | SMN1; SMN2DYRK1AHTTNPSR1ALDH1A1 | |
| SCHEMBL1500697 | 0.76 | SMN1; SMN2 (0.48) | SMN1; SMN2DYRK1AHTTNPSR1ALDH1A1 | |
| SCHEMBL13208465 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2DYRK1AHTTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080116789-A1 | 1, 5-NAPHTHYRIDINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE | CANON KABUSHIKI KAISHA (JP) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080116789-A1 | 1, 5-NAPHTHYRIDINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE | ARL1, NAP1L1, NAP1L4 | SMN1; SMN2 4483/4885DYRK1A 3122/4885HTT 3024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.