SCHEMBL4924290

SCHEMBL4924290

O=P(O)(O)C1=NC=CCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15904483 0.61
SCHEMBL3979258 0.61
Phosphoric Acid SCHEMBL29574309 0.55
Phosphoric Acid SCHEMBL28073320 0.49 CA2 (0.36)
SCHEMBL5800702 0.49
SCHEMBL4275773 0.48
SCHEMBL2872718 0.47
Phosphoric Acid SCHEMBL28867293 0.46
Phosphoric Acid SCHEMBL30434862 0.46 CA2 (0.50)
Phosphoric Acid SCHEMBL524872 0.46

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080076738-A1 Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds GILEAD SCIENCES, INC. 2008-03-27 US disclosed
US-20060116356-A1 Phosphonate analogs of HIV integrase inhibitor compounds GILEAD SCIENCES, INC. 2006-06-01 US disclosed