Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexene SCHEMBL9456974 | 0.89 | — | — | |
| Cyclopentene SCHEMBL8022284 | 0.89 | — | — | |
| Phosphoric Acid SCHEMBL27742219 | 0.86 | TSHR (0.32) | MMP2FDPS | |
| Phosphoric Acid SCHEMBL140393 | 0.74 | CA2 (0.56) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL1332284 | 0.74 | — | — | |
| Phosphoric Acid SCHEMBL8844890 | 0.74 | CA2 (0.56) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL3788505 | 0.74 | CA2 (0.56) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL36090 | 0.74 | CA2 (0.56) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL5907 | 0.74 | CA2 (0.56) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL897840 | 0.74 | CA2 (0.56) | CA2SLC34A1KDM4EMMP2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106047782-A | Microorganisms and methods for the biosynthesis of butadiene | 基因组股份公司 | 2016-10-26 | — | — | CN | claimed |
| CN-105189771-B | Steviol glycoside is effectively generated in the recombination host | 埃沃尔瓦公司 | 2019-11-05 | — | — | CN | disclosed |
| CN-105051195-B | Methods for increasing rebaudioside D and rebaudioside M production | 埃沃尔瓦公司 | 2019-09-06 | — | — | CN | disclosed |
| CN-105408339-B | Height-purity sweetleaf steviol glycoside | 谱赛科有限责任公司 | 2019-06-25 | — | — | CN | disclosed |
| CN-103080324-B | Microorganisms and methods for butadiene biosynthesis | 基因组股份公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-108474008-A | Maltose dependence degron, maltose responsive promoter stabilize construct and its purposes in generating non-decomposition metabolic compounds | 阿迈瑞斯公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-108474009-A | Maltose dependence degron, maltose responsive promoter stabilize construct and its purposes in generating non-decomposition metabolic compounds | 阿迈瑞斯公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-108396044-A | The recombinant production of steviol glycoside class | 埃沃尔瓦公司 | 2018-08-14 | — | — | CN | disclosed |
| CN-104540949-B | For stablizing the method for acetyl-coacetylase derivative compound generation | 阿迈瑞斯公司 | 2018-05-29 | — | — | CN | disclosed |
| CN-103732753-B | Recombinant Production of Steviol Glycosides | 埃沃尔瓦公司 | 2018-03-30 | — | — | CN | disclosed |
| CN-107750276-A | For improving the engineered microorganisms and method of crotons alcohol production | 基因组股份公司 | 2018-03-02 | — | — | CN | disclosed |
| CN-107613786-A | HEAT TREATMENT TO PRODUCE GLYCOSIDES | 嘉吉公司 | 2018-01-19 | — | — | CN | disclosed |
| CN-107105734-A | High Purity Steviol Glycosides | 谱赛科有限责任公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-103764818-B | The method and material of safflower compound are produced for recombinating | 埃沃尔瓦公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-106795523-A | Method for preparing rebaudioside I and application | 可口可乐公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-106191132-A | For the biosynthetic microorganism of butadiene and method | 基因组股份公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-106190995-A | (E) 4 hydroxyl 3 methyl 2 cyclobutenyl diphosphate synthase and encoding gene thereof and application | 西安电子科技大学 | 2016-12-07 | — | — | CN | disclosed |
| CN-106047782-A | Microorganisms and methods for the biosynthesis of butadiene | 基因组股份公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-103459602-B | Microorganisms and methods for butadiene biosynthesis | 基因组股份公司 | 2016-08-10 | — | — | CN | disclosed |