SCHEMBL4924307

SCHEMBL4924307

NC1=Cc2cccc3cc4ccccc4c1c23

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.45
CYP1A2 P05177 4/20 0.43
ERBB2 P04626 1/20 0.43
FYN P06241 1/20 0.43
MAOA P21397 1/20 0.43
ACHE P22303 1/20 0.43
AHR P35869 1/20 0.43
GAA P10253 2/20 0.40
MGAM O43451 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
NQO2 P16083 2/20 0.38
NQO1 P15559 1/20 0.37
HTR2A P28223 1/20 0.37
ALDH1A1 P00352 7/20 0.36
HSD17B10 Q99714 6/20 0.36
HPGD P15428 5/20 0.36
TSHR P16473 2/20 0.36
CYP3A4 P08684 2/20 0.36
KEAP1 Q14145 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21832124 0.79 CES1 (0.49) CES1CYP1A2ERBB2FYNMAOA
SCHEMBL218600 0.79 CES1 (0.45) CES1CYP1A2ERBB2FYNMAOA
SCHEMBL6542163 0.77 CES1 (0.44) CES1CYP1A2ERBB2FYNMAOA
SCHEMBL6542158 0.77 CYP1A2 (0.46) CES1CYP1A2ERBB2FYNMAOA
SCHEMBL30913181 0.75 CES1 (0.41) CES1CYP1A2ERBB2FYNMAOA
SCHEMBL7037670 0.72 ALDH1A1 (0.39) CYP1A2ALDH1A1HSD17B10HPGDTSHR
SCHEMBL21832147 0.71 CES1 (0.42) CES1CYP1A2ERBB2FYNMAOA
SCHEMBL27435879 0.71 CES1 (0.39) CES1CYP1A2ERBB2FYNMAOA
SCHEMBL29358751 0.70 CES1 (0.51) CES1CYP1A2ERBB2FYNMAOA
SCHEMBL6503129 0.70 CES1 (0.51) CES1CYP1A2ERBB2FYNMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200199481-A1 GREASE COMPOSITIONS HAVING CALCIUM SULFONATE AND POLYUREA THICKENERS EXXONMOBIL RES & ENG CO (US) 2020-06-25 US disclosed
WO-2020131440-A1 GREASE COMPOSITIONS HAVING CALCIUM SULFONATE AND POLYUREA THICKENERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-06-25 WO disclosed
EP-1840399-B1 COLLAPSIBLE COLUMN NSK LTD (JP) 2014-06-18 EP disclosed
CN-100591938-C Telescopic shaft NSK LTD 2010-02-24 CN disclosed
US-20080125231-A1 Telescopic Shaft NSK LTD. (JP) 2008-05-29 US disclosed
CN-101091069-A Collapsible column NSK LTD (JP) 2007-12-19 CN disclosed
EP-1840399-A1 COLLAPSIBLE COLUMN NSK Ltd., (JP) 2007-10-03 EP disclosed
CN-1259388-C Composition for organic electroluminescent device and organic electroluminescent device using the same TOYO INK MFG CO (JP) 2006-06-14 CN disclosed
US-20060073989-A1 Grease compostion for automobile electrical equipment auxiliary device and prelubricated rolling using the grease composition NSK LTD. (JP) 2006-04-06 US disclosed
US-6919301-B2 Grease composition and rolling apparatus NSK LTD. (JP) 2005-07-19 US disclosed
CN-1526002-A Composition for organic electroluminescence element and organic electroluminescence element using the same ��ī�����˹��ʽ���� 2004-09-01 CN disclosed
US-20030176298-A1 Grease composition and rolling apparatus NSK LTD. (JP) 2003-09-18 US disclosed