SCHEMBL27435879

SCHEMBL27435879

[c]1ccc(C2=Cc3cccc4cc5ccccc5c2c34)cc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.39
ERBB2 P04626 1/20 0.37
CYP1A2 P05177 1/20 0.37
FYN P06241 1/20 0.37
MAOA P21397 1/20 0.37
ACHE P22303 1/20 0.37
AHR P35869 1/20 0.37
NQO2 P16083 2/20 0.36
ALOX5 P09917 1/20 0.34
NQO1 P15559 1/20 0.33
NISCH Q9Y2I1 1/20 0.33
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
CASP1 P29466 1/20 0.30
HIF1A Q16665 1/20 0.30
HSD17B10 Q99714 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1370743 0.75 ALOX5 (0.50) CES1ERBB2CYP1A2FYNMAOA
SCHEMBL4977411 0.74 CES1 (0.43) CES1ERBB2CYP1A2FYNMAOA
SCHEMBL4924307 0.71 CES1 (0.45) CES1ERBB2CYP1A2FYNMAOA
SCHEMBL21832124 0.71 CES1 (0.49) CES1ERBB2CYP1A2FYNMAOA
SCHEMBL218600 0.71 CES1 (0.45) CES1ERBB2CYP1A2FYNMAOA
SCHEMBL8886149 0.71 MAPK1 (0.47) CES1CYP1A2ALDH1A1HPGDTSHR
SCHEMBL6542163 0.70 CES1 (0.44) CES1ERBB2CYP1A2FYNMAOA
SCHEMBL6542158 0.70 CYP1A2 (0.46) CES1ERBB2CYP1A2FYNMAOA
SCHEMBL30913181 0.68 CES1 (0.41) CES1ERBB2CYP1A2FYNMAOA
SCHEMBL9957739 0.67 NISCH (0.40) CES1CYP1A2NQO2ALOX5NISCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1125835-C Unsaturated ethylene copolymer, and rubber compositions contg. same MITSUI CHEMICAL IND CO LTD (JP) 2003-10-29 CN disclosed
CN-1259529-A Unsaturated ethylene copolymer, and rubber compositions contg. same MITSUI CHEMICAL IND CO LTD (JP) 2000-07-12 CN disclosed