Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | PAM | P19021 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5003265 | 0.91 | TSHR (0.52) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL4141159 | 0.89 | DGKA (0.44) | DGKATSHRLMNANAAANFKB1 | |
| SCHEMBL38542 | 0.89 | DGKA (0.44) | DGKATSHRLMNANAAANFKB1 | |
| SCHEMBL27179 | 0.89 | DGKA (0.44) | DGKATSHRLMNANAAANFKB1 | |
| SCHEMBL20542 | 0.89 | DGKA (0.44) | DGKATSHRLMNANAAANFKB1 | |
| SCHEMBL4662886 | 0.89 | DGKA (0.44) | DGKATSHRLMNANAAANFKB1 | |
| SCHEMBL11065777 | 0.89 | DGKA (0.44) | DGKATSHRLMNANAAANFKB1 | |
| SCHEMBL10346810 | 0.89 | DGKA (0.44) | DGKATSHRLMNANAAANFKB1 | |
| SCHEMBL134788 | 0.89 | DGKA (0.44) | DGKATSHRLMNANAAANFKB1 | |
| SCHEMBL4125398 | 0.89 | DGKA (0.44) | DGKATSHRLMNANAAANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080032940-A1 | METHODS FOR REDUCING ANTHRACYCLINE-INDUCED TOXICITY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-02-07 | — | — | US | disclosed |