Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4929137 | 0.90 | GPR119 (0.38) | NAMPTGPR119BCL2CYP1A2CYP2C9 | |
| SCHEMBL4932361 | 0.88 | CYP1A2 (0.38) | NAMPTGPR119BCL2CYP1A2CYP2C9 | |
| SCHEMBL4934933 | 0.84 | NAMPT (0.48) | NAMPTGPR119BCL2BECN1CNR1 | |
| SCHEMBL4931684 | 0.83 | KDM1A (0.43) | CYP2C9CYP2C19GRM5GRM1MGLL | |
| SCHEMBL5524902 | 0.82 | NAMPT (0.48) | NAMPTGPR119BCL2CYP1A2HTR2C | |
| SCHEMBL4935720 | 0.82 | HPGD (0.45) | CYP1A2CYP2C9CYP2C19MGLLCYP3A4 | |
| SCHEMBL4931192 | 0.82 | MGLL (0.45) | CYP1A2CYP2C9CYP2C19MGLLCYP3A4 | |
| SCHEMBL4932442 | 0.81 | CHRNA7 (0.39) | CYP1A2HTR2CCYP2C19GRM1MGLL | |
| SCHEMBL4931848 | 0.81 | CHRNA7 (0.46) | CYP1A2CYP2C9CYP2C19GRM5MGLL | |
| SCHEMBL4931713 | 0.81 | CHRNA7 (0.40) | CYP1A2CYP2C9CYP2C19MGLLCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064682-A1 | Pyrazole Derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-03-13 | — | — | US | disclosed |
| CN-1980912-A | Pyrazole derivatives | DAIICHI SEIYAKU CO (JP) | 2007-06-13 | — | — | CN | disclosed |
| EP-1762568-A1 | PYRAZOLE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064682-A1 | Pyrazole Derivatives | NAT1, AR, CBR3 | NAMPT 3346/4885GPR119 1933/4885BCL2 2316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.