Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.31 |
| ▸ | SLC16A1 | P53985 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4924531 | 1.00 | KMT2A (0.34) | KMT2AL3MBTL1BACE1SLC16A3SLC16A1 | |
| SCHEMBL4924527 | 1.00 | KMT2A (0.34) | KMT2AL3MBTL1BACE1SLC16A3SLC16A1 | |
| SCHEMBL4922174 | 0.89 | SLC16A3 (0.37) | BACE1SLC16A3SLC16A1 | |
| SCHEMBL4922185 | 0.89 | SLC16A3 (0.37) | BACE1SLC16A3SLC16A1 | |
| SCHEMBL4922169 | 0.89 | SLC16A3 (0.37) | BACE1SLC16A3SLC16A1 | |
| SCHEMBL4482579 | 0.88 | KMT2A (0.35) | KMT2AL3MBTL1SLC16A3SLC16A1KDM4E | |
| SCHEMBL14281499 | 0.88 | KMT2A (0.35) | KMT2AL3MBTL1SLC16A3SLC16A1KDM4E | |
| SCHEMBL4375418 | 0.88 | KMT2A (0.35) | KMT2AL3MBTL1SLC16A3SLC16A1KDM4E | |
| SCHEMBL4920388 | 0.84 | KMT2A (0.36) | KMT2AL3MBTL1BACE1KDM4EPKM | |
| SCHEMBL14281455 | 0.84 | KMT2A (0.34) | KMT2AL3MBTL1BACE1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015238-A1 | CYCLOALKYLMETHOXY-SUBSTITUTED ACETIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-01-17 | — | — | US | disclosed |
| US-7259177-B2 | Cycloalkylmethoxy-substituted acetic acid derivatives, processes for their preparation and their use as pharmaceuticals | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-08-21 | — | — | US | disclosed |
| US-20050101637-A1 | Cycloalkylmethoxy-substituted acetic acid derivatives, processes for their preparation and their use as pharmaceuticals | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015238-A1 | CYCLOALKYLMETHOXY-SUBSTITUTED ACETIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | GPR119, PC, ACADM | KMT2A 4433/4885L3MBTL1 4518/4885BACE1 1742/4885 |
| US-20050101637-A1 | Cycloalkylmethoxy-substituted acetic acid derivatives, processes for their preparation and their use as pharmaceuticals | GPR119, PC, CPT1A | KMT2A 4494/4885L3MBTL1 4572/4885BACE1 1971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.