Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 4/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4924653 | 0.71 | BRD4 (0.42) | BRD4TDP2GABRA5GABRA1CSF1R | |
| SCHEMBL4926630 | 0.70 | CSF1R (0.43) | BRD4GABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL4924658 | 0.69 | CSF1R (0.42) | BRD4GABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL4922991 | 0.69 | GABRG2 (0.43) | BRD4TDP2GABRG2GABRB3GABRA5 | |
| SCHEMBL25780703 | 0.65 | BRD4 (0.58) | BRD4TDP2GABRG2GABRB3GABRA5 | |
| SCHEMBL1495328 | 0.64 | BRD4 (0.60) | BRD4TDP2HSD17B10 | |
| SCHEMBL25780927 | 0.63 | BRD4 (0.56) | BRD4TDP2KDM4EHSD17B10GABRA2 | |
| SCHEMBL28472394 | 0.63 | BRD4 (0.61) | BRD4TDP2KDM4ECASP1HSD17B10 | |
| SCHEMBL29479606 | 0.62 | BRD4 (0.51) | BRD4TDP2GABRG2GABRB3GABRA5 | |
| SCHEMBL17517033 | 0.61 | BRD4 (0.41) | BRD4TDP2GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234335-A1 | Cyclohexene Compounds | GLAXO GROUP LIMITED (GB) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234335-A1 | Cyclohexene Compounds | C1R, CYP1B1, CYP2C9 | BRD4 1260/4885TDP2 3900/4885ACHE 1670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.