Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 3/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4926630 | 0.82 | CSF1R (0.43) | BRD4CSF1RMAPTNPSR1LMNA | |
| SCHEMBL4924658 | 0.81 | CSF1R (0.42) | BRD4CSF1RMAPTNPSR1LMNA | |
| SCHEMBL4922991 | 0.79 | GABRG2 (0.43) | BRD4TDP2MAPTNPSR1LMNA | |
| SCHEMBL1495328 | 0.75 | BRD4 (0.60) | BRD4TDP2MAPTNPSR1LMNA | |
| SCHEMBL4924644 | 0.71 | BRD4 (0.37) | BRD4TDP2CSF1RCDC7GABRA1 | |
| SCHEMBL25780703 | 0.71 | BRD4 (0.58) | BRD4TDP2GABRA1GABRA5CYP1A2 | |
| SCHEMBL25780927 | 0.69 | BRD4 (0.56) | BRD4TDP2MAPTNPSR1LMNA | |
| SCHEMBL16060393 | 0.68 | ACHE (0.41) | BRD4TDP2MAPTNPSR1CDC7 | |
| SCHEMBL27492257 | 0.68 | BRD4 (0.58) | BRD4TDP2MAPTCTSACYP1A2 | |
| SCHEMBL27968857 | 0.68 | TSHR (0.58) | MAPTLMNACYP1A2POLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234335-A1 | Cyclohexene Compounds | GLAXO GROUP LIMITED (GB) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234335-A1 | Cyclohexene Compounds | C1R, CYP1B1, CYP2C9 | BRD4 1260/4885TDP2 3900/4885CSF1R 2002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.