SCHEMBL4925514

SCHEMBL4925514

C=C1C(N)=Cc2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.40
DRD4 P21917 2/20 0.40
ALDH1A1 P00352 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
NSD2 O96028 1/20 0.35
PTPN1 P18031 1/20 0.35
HKDC1 Q2TB90 1/20 0.35
SLC2A1 P11166 1/20 0.32
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
CDC25A P30304 1/20 0.31
CDC25B P30305 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5969975 0.79
Hydrochloric Acid SCHEMBL5969933 0.77 PTPN1 (0.44) ALDH1A1L3MBTL1NSD2PTPN1HKDC1
SCHEMBL19264047 0.71 DRD2 (0.43) DRD2DRD4ALDH1A1CDC25ACDC25B
SCHEMBL6233550 0.70 CDC25B (0.52) ALDH1A1L3MBTL1NSD2PTPN1HKDC1
SCHEMBL30003397 0.70 CDC25B (0.52) ALDH1A1L3MBTL1NSD2PTPN1HKDC1
SCHEMBL9204207 0.69 LMNA (0.48) DRD2DRD4ALDH1A1PTPN1CDC25B
SCHEMBL5712411 0.68 DRD2 (0.45) DRD2DRD4ALDH1A1PTPN1NR1H2
SCHEMBL1965626 0.64
Hydrazine SCHEMBL11361257 0.62 KMT2A (0.53) ALDH1A1L3MBTL1NSD2CDC25BHSD17B10
SCHEMBL10354666 0.62 ABCG2 (0.39) DRD2DRD4ALDH1A1L3MBTL1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200199481-A1 GREASE COMPOSITIONS HAVING CALCIUM SULFONATE AND POLYUREA THICKENERS EXXONMOBIL RES & ENG CO (US) 2020-06-25 US disclosed
WO-2020131440-A1 GREASE COMPOSITIONS HAVING CALCIUM SULFONATE AND POLYUREA THICKENERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-06-25 WO disclosed
EP-1840399-B1 COLLAPSIBLE COLUMN NSK LTD (JP) 2014-06-18 EP disclosed
US-20080125231-A1 Telescopic Shaft NSK LTD. (JP) 2008-05-29 US disclosed
EP-1840399-A1 COLLAPSIBLE COLUMN NSK Ltd., (JP) 2007-10-03 EP disclosed
US-20060073989-A1 Grease compostion for automobile electrical equipment auxiliary device and prelubricated rolling using the grease composition NSK LTD. (JP) 2006-04-06 US disclosed
US-6919301-B2 Grease composition and rolling apparatus NSK LTD. (JP) 2005-07-19 US disclosed
US-20030176298-A1 Grease composition and rolling apparatus NSK LTD. (JP) 2003-09-18 US disclosed