Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.57 |
| ▸ | BMP1 | P13497 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP7 | P09237 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14260749 | 1.00 | MMP1 (0.60) | MMP1HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL4925285 | 1.00 | MMP1 (0.60) | MMP1HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL14260750 | 1.00 | MMP1 (0.60) | MMP1HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL14260672 | 0.89 | HDAC3 (0.60) | MMP1HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL1233724 | 0.84 | HDAC3 (0.67) | MMP1HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL7138854 | 0.84 | HDAC3 (0.67) | MMP1HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL1233776 | 0.84 | BMP1 (0.68) | MMP1HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL1233906 | 0.84 | HDAC1 (0.66) | MMP1HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL14260747 | 0.83 | HDAC1 (0.67) | HDAC1HDAC3HDAC2HDAC8HDAC4 | |
| SCHEMBL1231831 | 0.83 | HDAC3 (0.63) | MMP1HDAC1HDAC3HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | S*BIO PTE LTD. (SG) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | HDAC1, HDAC3, HDAC4 | MMP1 959/4885HDAC1 1/4885HDAC3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.