Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 9/20 | 0.62 |
| ▸ | CSNK2B | P67870 | 9/20 | 0.62 |
| ▸ | CSNK2A1 | P68400 | 9/20 | 0.62 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | TNKS | O95271 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.52 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 2/20 | 0.46 |
| ▸ | GABRD | O14764 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649989 | 0.89 | CSNK2A2 (0.62) | CSNK2A2CSNK2BCSNK2A1TNKSCYP1A1 | |
| SCHEMBL15231415 | 0.85 | CSNK2A2 (0.65) | CSNK2A2CSNK2BCSNK2A1MAOBTNKS | |
| SCHEMBL4649950 | 0.85 | TNKS (0.61) | CSNK2A2CSNK2BCSNK2A1MAOBTNKS | |
| SCHEMBL24046751 | 0.80 | CSNK2A2 (0.67) | CSNK2A2CSNK2BCSNK2A1CYP1A1CYP1A2 | |
| SCHEMBL11802722 | 0.78 | ESR1 (0.55) | CSNK2A2CSNK2BCSNK2A1MAOB | |
| SCHEMBL24046919 | 0.77 | CSNK2A2 (0.50) | CSNK2A2CSNK2BCSNK2A1TNKSCYP1A1 | |
| SCHEMBL21959063 | 0.76 | CSNK2A2 (0.48) | CSNK2A2CSNK2BCSNK2A1MAOBCYP1A1 | |
| SCHEMBL21886746 | 0.74 | CSNK2A2 (0.56) | CSNK2A2CSNK2BCSNK2A1MAOBTNKS | |
| SCHEMBL16342832 | 0.72 | ABCG2 (0.66) | CSNK2A2CSNK2BCSNK2A1MAOB | |
| SCHEMBL4650552 | 0.72 | CSNK2A2 (0.74) | CSNK2A2CSNK2BCSNK2A1MAOBTNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287374-A1 | BREAST CANCER-RESISTANT PROTEIN INHIBITOR | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2008-11-20 | — | — | US | disclosed |
| US-20060135445-A1 | Breast cancer-resistant protein inhibitor | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2006-06-22 | — | — | US | disclosed |
| EP-1591112-A1 | BREAST CANCER-RESISTANT PROTEIN INHIBITOR | Kabushiki Kaisha Yakult Honsha (JP) | 2005-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135445-A1 | Breast cancer-resistant protein inhibitor | ABCC1, BCR, BRCA1 | CSNK2A2 2298/4885CSNK2B 2245/4885CSNK2A1 2290/4885 |
| US-20080287374-A1 | BREAST CANCER-RESISTANT PROTEIN INHIBITOR | ABCC1, BCR, BRCA1 | CSNK2A2 2298/4885CSNK2B 2245/4885CSNK2A1 2290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.