Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 3/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.61 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.57 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.57 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 8/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | PDE5A | O76074 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649989 | 0.89 | CSNK2A2 (0.62) | TNKSADORA3CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL15231415 | 0.85 | CSNK2A2 (0.65) | TNKSCSNK2A2CSNK2BCSNK2A1CYP1B1 | |
| SCHEMBL4925702 | 0.85 | CSNK2A2 (0.62) | TNKSCSNK2A2CSNK2BCSNK2A1CYP1B1 | |
| SCHEMBL24046751 | 0.77 | CSNK2A2 (0.67) | CSNK2A2CSNK2BCSNK2A1CYP1B1CYP1A1 | |
| SCHEMBL24046919 | 0.76 | CSNK2A2 (0.50) | TNKSADORA3CSNK2A2CSNK2BCSNK2A1 | |
| 6-Chloroflavone SCHEMBL4649891 | 0.76 | TNKS (1.00) | TNKSADORA3CYP1B1CYP19A1TP53 | |
| SCHEMBL7123231 | 0.76 | CA1 (0.44) | TNKSADORA3CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL31632254 | 0.76 | GABRP (0.61) | TNKSADORA3CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL30000854 | 0.74 | TNKS (0.69) | TNKSADORA3CYP1B1CYP1A2CYP19A1 | |
| SCHEMBL3067421 | 0.74 | ERAP1 (0.52) | CSNK2A2CSNK2BCSNK2A1CYP1B1CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| EP-2730431-B1 | Rubber composition and tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2017-06-28 | — | — | EP | disclosed |
| US-20140135433-A1 | TIRE WITH RUBBER CONTAINING FLAVONE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2014-05-15 | — | — | US | disclosed |
| EP-2730431-A1 | Rubber composition and tire with rubber containing flavone | The Goodyear Tire & Rubber Company (US) | 2014-05-14 | — | — | EP | disclosed |
| EP-1391327-B1 | Tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2008-09-03 | — | — | EP | disclosed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | disclosed |
| EP-1391327-A1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2003057210-A1 | COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | TNKS 2038/4885ADORA3 4438/4885CSNK2A2 3078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.