Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.33 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35730 | 0.92 | — | — | |
| SCHEMBL9863629 | 0.91 | USP2 (0.35) | USP2MEN1TP53KMT2ALMNA | |
| SCHEMBL10978078 | 0.89 | USP2 (0.33) | USP2MEN1TP53KMT2ALMNA | |
| SCHEMBL7622613 | 0.86 | — | — | |
| SCHEMBL5855479 | 0.85 | — | — | |
| SCHEMBL5507251 | 0.82 | NAAA (0.34) | USP2MEN1TP53KMT2ALMNA | |
| SCHEMBL5503115 | 0.82 | CA2 (0.33) | TSHRCYP3A4 | |
| SCHEMBL12559776 | 0.82 | — | — | |
| SCHEMBL643922 | 0.82 | — | — | |
| SCHEMBL4914719 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214769-A1 | Polyurethanes with an Asker C-Hardness of Between 1 and 70 | BASF AKTIENGESELLSCHAFT (DE) | 2008-09-04 | — | — | US | disclosed |
| US-5641851-A | REACTING ALIPHATIC AND/OR CYCLOALIPHATIC DIISOCYANATES WITH WATER IN FORM OF STEAM IN PRESENCE OF ACIDIC CATALYST SELECTED FROM PHOSPHORIC ACID, ESTERS THEREOF AND/OR HYDROGEN SULFATES | BASF AKTIENGESELLSCHAFT (DE) | 1997-06-24 | — | — | US | disclosed |