Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.38 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820720 | 0.88 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL18052240 | 0.87 | HTR2A (0.47) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL18052179 | 0.87 | HTR2A (0.47) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL3025283 | 0.87 | HTR2A (0.47) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL14975401 | 0.84 | SLC12A2 (0.45) | SLC12A2SLC12A5CA12CA1CA9 | |
| SCHEMBL14975403 | 0.84 | SLC12A2 (0.45) | SLC12A2SLC12A5CA12CA1CA9 | |
| SCHEMBL6221876 | 0.81 | KMT2A (0.49) | SLC12A2SLC12A5CA12CA1CA9 | |
| SCHEMBL2098311 | 0.81 | KMT2A (0.49) | SLC12A2SLC12A5CA12CA1CA9 | |
| SCHEMBL4065055 | 0.81 | KMT2A (0.49) | SLC12A2SLC12A5CA12CA1CA9 | |
| SCHEMBL2929267 | 0.80 | SLC12A2 (0.54) | SLC12A2SLC12A5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016811-A2 | AMINOPIPERIDINES AND REALTED COMPOUNDS | NEUROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |