Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.41 |
| ▸ | PTGES | O14684 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4922586 | 0.92 | PPARG (0.40) | PPARGPTGESPPARAPTGDR | |
| SCHEMBL4924514 | 0.90 | PTGES (0.41) | PPARGPTGESPPARA | |
| SCHEMBL4912679 | 0.88 | PPARG (0.42) | PPARGPTGESPPARA | |
| SCHEMBL4918280 | 0.87 | PPARG (0.41) | PPARGPTGESPPARA | |
| SCHEMBL4914614 | 0.86 | PPARG (0.48) | PPARGPTGESPPARA | |
| SCHEMBL3002052 | 0.85 | PPARG (0.45) | PPARGPTGESPPARA | |
| SCHEMBL4924017 | 0.82 | PPARG (0.45) | PPARGPTGESPPARA | |
| SCHEMBL4926810 | 0.82 | PPARG (0.42) | PPARGPTGESPPARA | |
| SCHEMBL4923431 | 0.80 | PTGES (0.40) | PPARGPTGESPPARA | |
| SCHEMBL4922575 | 0.80 | PPARG (0.41) | PPARGPTGESPPARAPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249091-A1 | Indoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249091-A1 | Indoles Useful in the Treatment of Inflammation | IDO1, IDO2, ARG1 | PPARG 2586/4885PTGES 35/4885PPARA 3339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.