Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796601 | 1.00 | CTSS (0.54) | CTSSCTSKPTPN1SCN9AATM | |
| SCHEMBL5796611 | 1.00 | CTSS (0.54) | CTSSCTSKPTPN1SCN9AATM | |
| SCHEMBL10054505 | 0.86 | SCN9A (0.42) | CTSSCTSKPTPN1SCN9AATM | |
| SCHEMBL4663069 | 0.84 | CTSS (0.57) | CTSSCTSKPTPN1SCN9AATM | |
| SCHEMBL4922943 | 0.84 | CTSS (0.60) | CTSSCTSKPTPN1SCN9AATM | |
| SCHEMBL4922934 | 0.84 | CTSS (0.60) | CTSSCTSKPTPN1SCN9AATM | |
| SCHEMBL7029037 | 0.84 | CTSS (0.60) | CTSSCTSKPTPN1SCN9AATM | |
| SCHEMBL8098623 | 0.83 | ATM (0.64) | CTSSCTSKATMCYP3A4PPARG | |
| SCHEMBL26999155 | 0.83 | ATM (0.64) | CTSSCTSKATMCYP3A4PPARG | |
| SCHEMBL17015 | 0.82 | CTSS (0.60) | CTSSCTSKPTPN1SCN9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275086-A1 | Dpp-Iv Inhibitors | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2008-11-06 | — | — | US | disclosed |
| US-20080275086-A1 | Dpp-Iv Inhibitors | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2008-11-06 | — | — | US | disclosed |
| US-20080275086-A1 | Dpp-Iv Inhibitors | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2008-11-06 | — | — | US | disclosed |
| EP-1702916-A1 | DPP-IV inhibitors | Santhera Pharmaceuticals (Schweiz) GmbH (CH) | 2006-09-20 | — | — | EP | disclosed |
| EP-1702916-A1 | DPP-IV inhibitors | Santhera Pharmaceuticals (Schweiz) GmbH (CH) | 2006-09-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275086-A1 | Dpp-Iv Inhibitors | DPP4, DPP7, DPP3 | CTSS 271/4885CTSK 124/4885PTPN1 335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.