Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796611 | 1.00 | CTSS (0.54) | CTSSCTSKPTPN1SCN9AATM | |
| SCHEMBL4926944 | 1.00 | CTSS (0.54) | CTSSCTSKPTPN1SCN9AATM | |
| SCHEMBL10054505 | 0.86 | SCN9A (0.42) | CTSSCTSKPTPN1SCN9AATM | |
| SCHEMBL4663069 | 0.84 | CTSS (0.57) | CTSSCTSKPTPN1SCN9AATM | |
| SCHEMBL4922943 | 0.84 | CTSS (0.60) | CTSSCTSKPTPN1SCN9AATM | |
| SCHEMBL4922934 | 0.84 | CTSS (0.60) | CTSSCTSKPTPN1SCN9AATM | |
| SCHEMBL7029037 | 0.84 | CTSS (0.60) | CTSSCTSKPTPN1SCN9AATM | |
| SCHEMBL8098623 | 0.83 | ATM (0.64) | CTSSCTSKATMCYP3A4PPARG | |
| SCHEMBL26999155 | 0.83 | ATM (0.64) | CTSSCTSKATMCYP3A4PPARG | |
| SCHEMBL17015 | 0.82 | CTSS (0.60) | CTSSCTSKPTPN1SCN9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1702916-A1 | DPP-IV inhibitors | Santhera Pharmaceuticals (Schweiz) GmbH (CH) | 2006-09-20 | — | — | EP | disclosed |