Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.82 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.77 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | TERT | O14746 | 3/20 | 0.68 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | BLM | P54132 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | FABP4 | P15090 | 2/20 | 0.68 |
| ▸ | PPARG | P37231 | 2/20 | 0.68 |
| ▸ | PPARD | Q03181 | 2/20 | 0.68 |
| ▸ | PPARA | Q07869 | 2/20 | 0.68 |
| ▸ | GMNN | O75496 | 1/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4795104 | 1.00 | PLA2G4A (0.82) | PLA2G4APLA2G2AEPHX2KDM4ETERT | |
| SCHEMBL2770529 | 0.91 | PLA2G4A (1.00) | PLA2G4APLA2G2AEPHX2PTPN1HSD17B10 | |
| SCHEMBL1877382 | 0.91 | PLA2G4A (1.00) | PLA2G4APLA2G2AEPHX2PTPN1HSD17B10 | |
| SCHEMBL13193162 | 0.86 | EPHX2 (1.00) | EPHX2TERTPTPN1MAPTBLM | |
| SCHEMBL4777435 | 0.86 | EPHX2 (0.68) | PLA2G4APLA2G2AEPHX2KDM4EFAAH | |
| SCHEMBL4927930 | 0.86 | EPHX2 (0.68) | PLA2G4APLA2G2AEPHX2KDM4EFAAH | |
| SCHEMBL9947772 | 0.85 | EPHX2 (0.94) | EPHX2KDM4ETERTPTPN1MAPT | |
| SCHEMBL15297170 | 0.85 | EPHX2 (0.94) | EPHX2KDM4ETERTPTPN1MAPT | |
| SCHEMBL21983254 | 0.85 | EPHX2 (0.94) | EPHX2KDM4ETERTPTPN1MAPT | |
| SCHEMBL15297199 | 0.85 | EPHX2 (0.94) | EPHX2KDM4ETERTPTPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080319065-A1 | Systemic and Intrathecal Effects of a Novel Series of Phospholipase A2 Inhibitors on Hyperalgesia and Spinal Pge2 Release | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-12-25 | — | — | US | disclosed |
| CN-101291666-A | Systemic and intrathecal effects of a novel series of phospholipase a2 inhibitors on hyperalgesia and spinal pge2 release | UNIV CALIFORNIA (US) | 2008-10-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319065-A1 | Systemic and Intrathecal Effects of a Novel Series of Phospholipase A2 Inhibitors on Hyperalgesia and Spinal Pge2 Release | PLA2G4A, PLA2G4B, PLA2G2A | PLA2G4A 1/4885PLA2G2A 3/4885EPHX2 140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.