Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SCN4A | P35499 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3912413 | 0.87 | MAPT (0.39) | MAPTGAAALDH1A1MAPK1LMNA | |
| SCHEMBL3222750 | 0.76 | MAPT (0.41) | MAPTGAAALDH1A1MAPK1LMNA | |
| SCHEMBL1902569 | 0.73 | MAPT (0.47) | MAPTGAATDP1ALDH1A1MAPK1 | |
| SCHEMBL28059865 | 0.71 | MAPT (0.43) | MAPTGAAALDH1A1MAPK1MEN1 | |
| SCHEMBL31448339 | 0.71 | MAPT (0.43) | MAPTGAAALDH1A1MAPK1MEN1 | |
| SCHEMBL4796337 | 0.70 | MAPT (0.42) | MAPTGAATDP1ALDH1A1MAPK1 | |
| SCHEMBL29896250 | 0.70 | MAPT (0.42) | MAPTGAATDP1ALDH1A1MAPK1 | |
| SCHEMBL9782872 | 0.69 | MAPT (0.41) | MAPTGAAALDH1A1MAPK1LMNA | |
| SCHEMBL984966 | 0.69 | MAPT (0.41) | MAPTGAATDP1ALDH1A1MAPK1 | |
| SCHEMBL7223112 | 0.69 | GAA (0.34) | MAPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080026427-A1 | HUMAN cDNAs AND PROTEINS AND USES THEREOF | SERONO GENETICS INSTITUTE S.A. (FR) | 2008-01-31 | — | — | US | disclosed |
| US-20070292885-A1 | HUMAN CDNAS AND PROTEINS AND USES THEREOF | GENSET, S.A. (FR) | 2007-12-20 | — | — | US | disclosed |
| EP-1867633-A1 | Polyamine analogues as therapeutic and diagnostic agents | MediQuest Therapeutics, Inc. (US) | 2007-12-19 | — | — | EP | disclosed |
| US-7291495-B2 | β-Secretase variant | SERONO GENETICS INSTITUTE S.A. (FR) | 2007-11-06 | — | — | US | disclosed |
| US-7285631-B2 | Human cDNAs and proteins and uses thereof | SERONO GENETICS INSTITUTE S.A. (FR) | 2007-10-23 | — | — | US | disclosed |
| US-7271243-B2 | Full-length human cDNAs encoding potentially secreted proteins | SERONO GENETICS INSTITUTE S.A. (FR) | 2007-09-18 | — | — | US | disclosed |
| US-7208528-B1 | Polyamine analogues as therapeutic and diagnostic agents | MEDIQUEST THERAPEUTICS, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| US-20070015144-A9 | Human cDNAs and proteins and uses thereof | GENSET, S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-7160923-B1 | Polyamine analogues as therapeutic and diagnostic agents | MEDIQUEST THERAPEUTICS, INC. (US) | 2007-01-09 | — | — | US | disclosed |
| US-7122629-B2 | Human cDNAs and proteins and uses thereof | SERONO GENETICS INSTITUTE SA (FR) | 2006-10-17 | — | — | US | disclosed |
| WO-2003014151-A2 | HUMAN SECRETED PROTEINS, THEIR ENCODING POLYNUCLEOTIDES, AND USES THEREOF | GENSET S.A. (FR) | 2003-02-20 | — | — | WO | disclosed |
| US-20030027248-A1 | Human cDNAs and proteins and uses thereof | GENSET, S.A. (FR) | 2003-02-06 | — | — | US | disclosed |
| US-20030027161-A1 | Human cDNAs and proteins and uses thereof | GENSET, S.A. (FR) | 2003-02-06 | — | — | US | disclosed |
| WO-2002094864-A2 | HUMAN CDNAS AND PROTEINS AND USES THEREOF | GENSET S.A. (FR) | 2002-11-28 | — | — | WO | disclosed |
| US-20020102604-A1 | Full-length human cDNAs encoding potentially secreted proteins | SERONO GENETICS INSTITUTE S.A. (FR) | 2002-08-01 | — | — | US | disclosed |
| WO-2001092218-A2 | POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS | ORIDIGM CORPORATION (US) | 2001-12-06 | — | — | WO | disclosed |
| EP-1085011-A1 | Novel polyamine analogues as therapeutic and diagnostic agents | ORIDIGM CORPORATION (US) | 2001-03-21 | — | — | EP | disclosed |
| US-6172261-B1 | BIOSYNTHESIS USING CHAIN EXTENSION | ORIDIGM CORPORATION | 2001-01-09 | — | — | US | disclosed |
| EP-1001927-A2 | NOVEL POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS | ORIDIGM CORPORATION (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999003823-A2 | NOVEL POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS | ORIDIGM CORPORATION (US) | 1999-01-28 | — | — | WO | disclosed |