SCHEMBL984966

SCHEMBL984966

CC1(C(=O)O)C=Cc2ccccc2N1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.41
GAA P10253 3/20 0.41
SMN1; SMN2 Q16637 6/20 0.35
RAB9A P51151 3/20 0.35
P2RX4 Q99571 1/20 0.35
ALDH1A1 P00352 8/20 0.33
KDM4E B2RXH2 6/20 0.33
ALOX15 P16050 2/20 0.33
HSD17B10 Q99714 2/20 0.33
HPGD P15428 2/20 0.33
NPC1 O15118 2/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
POLB P06746 1/20 0.33
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
LMNA P02545 1/20 0.32
TGM2 P21980 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3208190 0.83 MAPT (0.38) MAPTGAASMN1; SMN2RAB9AP2RX4
Lithium Ion SCHEMBL984533 0.83 MAPT (0.38) MAPTGAASMN1; SMN2RAB9AP2RX4
SCHEMBL31448339 0.79 MAPT (0.43) MAPTGAASMN1; SMN2RAB9AP2RX4
SCHEMBL28059865 0.79 MAPT (0.43) MAPTGAASMN1; SMN2RAB9AP2RX4
SCHEMBL1284871 0.78 CES1 (0.36) SMN1; SMN2ALDH1A1MEN1TP53KMT2A
SCHEMBL4796337 0.77 MAPT (0.42) MAPTGAASMN1; SMN2RAB9AP2RX4
SCHEMBL29896250 0.77 MAPT (0.42) MAPTGAASMN1; SMN2RAB9AP2RX4
SCHEMBL9782872 0.76 MAPT (0.41) MAPTGAASMN1; SMN2RAB9AP2RX4
SCHEMBL3912413 0.75 MAPT (0.39) MAPTGAASMN1; SMN2RAB9AP2RX4
SCHEMBL1285713 0.74 MAPT (0.46) MAPTGAASMN1; SMN2RAB9AP2RX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070254183-A1 Electroluminescent materials and deivces MERCK PATENT GMBH (DE) 2007-11-01 US claimed
CN-119856682-A Creation and identification method of macadimia nut excellent drought-enduring germplasm 广西壮族自治区亚热带作物研究所(广西亚热带农产品加工研究所) 2025-04-22 CN disclosed
CN-111183192-B Antistatic powder coating composition 株式会社KCC 2022-06-07 CN disclosed
CN-111183129-A Novel anthranilic acid compound, Pin1 inhibitor using same, and therapeutic agent for inflammatory disease and cancer 国立大学法人广岛大学 2020-05-19 CN disclosed
US-8507896-B2 Compounds having electroluminescent or electron transport properties MERCK PATENT GMBH (DE) 2013-08-13 US disclosed
US-20110006295-A1 COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES MERCK PATENT GMBH 2011-01-13 US disclosed
EP-2250151-A1 COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES Merck Patent GmbH (DE) 2010-11-17 EP disclosed
WO-2009112854-A1 COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES MERCK PATENT GMBH (DE) 2009-09-17 WO disclosed
CN-1233180-A Treatment of the common cold or allergic rhinitis LILLY CO ELI (US) 1999-10-27 CN disclosed
EP-0490200-B1 Derivatives of quinoline carboxylic acid BASF AG (DE) 1996-02-28 EP disclosed
EP-0388620-B1 Process for the preparation of o-carboxypyridyl- and o-carboxyquinolylimidazolinones AMERICAN CYANAMID CO (US) 1994-11-02 EP disclosed
US-5214146-A Color formers for pressure sensitive recording materials BASF AKTIENGESELLSCHAFT (DE) 1993-05-25 US disclosed
EP-0388620-A1 Process for the preparation of o-carboxypyridyl- and o-carboxyquinolylimidazolinones AMERICAN CYANAMID COMPANY (US) 1990-09-26 EP disclosed
US-4925944-A CONDENSATION AND CYCLIZATION IN AROMATIC SOLVENT AND SULFUR; ONE STEP; HERBICIDES AMERICAN CYANAMID COMPANY (US) 1990-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110006295-A1 COMPOUNDS HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES NR2E3, NR4A2, NR4A3 MAPT 3534/4885GAA 4048/4885SMN1; SMN2 1611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.