Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29896250 | 1.00 | MAPT (0.42) | MAPTGAARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL31448339 | 0.80 | MAPT (0.43) | MAPTGAARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28059865 | 0.80 | MAPT (0.43) | MAPTGAARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL984966 | 0.77 | MAPT (0.41) | MAPTGAARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL9782872 | 0.77 | MAPT (0.41) | MAPTGAARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL3912413 | 0.76 | MAPT (0.39) | MAPTGAARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL6431986 | 0.73 | MAPT (0.37) | MAPTGAARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL1285713 | 0.72 | MAPT (0.46) | MAPTGAARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL31305217 | 0.71 | MAPT (0.35) | MAPTGAARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL3222750 | 0.70 | MAPT (0.41) | MAPTGAARAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1105666-A | Novel diazabicycloalkenes and processes for the preparation thereof | KOREA RES INST CHEM TECH (KR) | 1995-07-26 | — | — | CN | claimed |
| EP-2836483-A1 | ANTI-MALARIAL AGENTS | University Of Dundee (GB) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013153357-A1 | ANTI-MALARIAL AGENTS | UNIVERSITY OF DUNDEE (GB) | 2013-10-17 | — | — | WO | disclosed |
| US-7399434-B2 | Rare metal compounds and mixtures of these | HONEYWELL INTERNATIONAL INC (US) | 2008-07-15 | — | — | US | disclosed |
| CN-1329399-C | Rare earth metal compounds and mixtures of these | HONEYWELL SPECIALTY CHEMICALS (DE) | 2007-08-01 | — | — | CN | disclosed |
| US-7198732-B2 | Rare earth metal compounds and mixtures of these | HONEYWELL INTERNATIONAL INC. (US) | 2007-04-03 | — | — | US | disclosed |
| US-20070051929-A1 | Rare metal compounds and mixtures of these | HONEYWELL INTERNATIONAL INC. (US) | 2007-03-08 | — | — | US | disclosed |
| CN-1608072-A | Rare earth metal compounds and mixtures thereof | HONEYWELL SPECIALTY CHEMICALS (DE) | 2005-04-20 | — | — | CN | disclosed |
| EP-1456213-B1 | RARE EARTH METAL COMPOUNDS AND MIXTURES OF THESE | HONEYWELL SPECIALTY CHEMICALS (DE) | 2005-03-30 | — | — | EP | disclosed |
| US-20040262575-A1 | Rare earth metal compounds and mixtures of these | POTRAWA THOMAS | 2004-12-30 | — | — | US | disclosed |
| EP-1456213-A1 | RARE EARTH METAL COMPOUNDS AND MIXTURES OF THESE | Honeywell Specialty Chemicals Seelze GmbH (DE) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053980-A1 | RARE EARTH METAL COMPOUNDS AND MIXTURES OF THESE | HONEYWELL SPECIALITY CHEMICALS SEELZE GMBH (DE) | 2003-07-03 | — | — | WO | disclosed |
| CN-1105666-A | Novel diazabicycloalkenes and processes for the preparation thereof | KOREA RES INST CHEM TECH (KR) | 1995-07-26 | — | — | CN | disclosed |
| CN-1024415-C | Process for preparing benzoic acid derivatives | BAYER AG (DE) | 1994-05-04 | — | — | CN | disclosed |
| CN-1012958-B | PROCESS FOR PREPARATION OF 2-HYDROXY QUINOLINE CARBOXYLIC ACID DERIVATIVES | KYORIN SEIYAKU KK (JP) | 1991-06-26 | — | — | CN | disclosed |
| US-4767698-A | PHOTOSTABILITY, HEAT RESISTANCE | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1988-08-30 | — | — | US | disclosed |
| CN-87106482-A | Process for preparing benzoic acid derivatives | — | 1988-03-30 | — | — | CN | disclosed |
| CN-85106674-A | The preparation method of 2-hydroxy quinoline carboxylic acid derivatives | — | 1986-07-16 | — | — | CN | disclosed |
| CN-85106674-A | The preparation method of 2-hydroxy quinoline carboxylic acid derivatives | — | 1986-07-16 | — | — | CN | disclosed |
| CN-85106674-A | The preparation method of 2-hydroxy quinoline carboxylic acid derivatives | — | 1986-07-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040262575-A1 | Rare earth metal compounds and mixtures of these | SOD1, ERCC4, ERCC1 | MAPT 237/4885GAA 298/4885RAB9A 646/4885 |
| US-20070051929-A1 | Rare metal compounds and mixtures of these | RUVBL2, SOD1, MSH6 | MAPT 256/4885GAA 215/4885RAB9A 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.