Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2564990 | 0.89 | CASP3 (0.53) | HTTKMT2ACASP3UTS2R | |
| SCHEMBL18669155 | 0.83 | KMT2A (0.75) | HTTKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL4854039 | 0.80 | NR1H3 (0.62) | HTTALDH1A1MAPTKMT2ACASP3 | |
| SCHEMBL14165342 | 0.79 | KMT2A (0.44) | HTTKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL14165572 | 0.79 | KDM4E (0.45) | HTTKDM4EPOLBKMT2AL3MBTL1 | |
| SCHEMBL15906128 | 0.78 | HTT (0.50) | HTTKDM4EPOLBMAPTMAPK1 | |
| SCHEMBL10926180 | 0.78 | CASP3 (0.56) | HTTMAPTHPGDMAPK1KMT2A | |
| SCHEMBL6336921 | 0.77 | CASP3 (0.58) | HTTKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL2030026 | 0.77 | ALDH1A1 (0.55) | HTTKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL3024201 | 0.77 | CASP3 (0.58) | HTTKDM4EALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139493-A1 | Bi- or Tetra-Guanidino-Biphenyl Compounds as Small Molecule Carriers | UCL BUSINESS PLC (GB) | 2008-06-12 | — | — | US | disclosed |
| US-20080139493-A1 | Bi- or Tetra-Guanidino-Biphenyl Compounds as Small Molecule Carriers | UCL BUSINESS PLC (GB) | 2008-06-12 | — | — | US | disclosed |
| US-20080139493-A1 | Bi- or Tetra-Guanidino-Biphenyl Compounds as Small Molecule Carriers | UCL BUSINESS PLC (GB) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139493-A1 | Bi- or Tetra-Guanidino-Biphenyl Compounds as Small Molecule Carriers | CBR3, CBR1, KCNQ3 | HTT 1591/4885KDM4E 1082/4885MEN1 1701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.