Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3160520 | 0.98 | MAPT (0.55) | MAPTABCC4TSHRSMN1; SMN2PRMT1 | |
| SCHEMBL254214 | 0.98 | MAPT (0.55) | MAPTABCC4TSHRSMN1; SMN2PRMT1 | |
| SCHEMBL614518 | 0.94 | MAPT (0.48) | MAPTABCC4TSHRSMN1; SMN2PRMT1 | |
| Adipic Acid SCHEMBL27737322 | 0.89 | MAPT (0.58) | MAPTABCC4TSHRSMN1; SMN2PRMT1 | |
| Adipic Acid SCHEMBL7106709 | 0.89 | NFKB1 (0.52) | MAPTABCC4TSHRSMN1; SMN2PRMT1 | |
| SCHEMBL4616389 | 0.86 | MAPT (0.41) | MAPTABCC4TSHRSMN1; SMN2LMNA | |
| SCHEMBL253528 | 0.85 | — | — | |
| SCHEMBL3435875 | 0.83 | MAPT (0.42) | MAPTABCC4TSHRSMN1; SMN2LMNA | |
| SCHEMBL8856051 | 0.82 | KDM4E (0.43) | MAPTABCC4TSHRSMN1; SMN2LMNA | |
| SCHEMBL16340122 | 0.81 | KDM4E (0.42) | MAPTABCC4TSHRSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275028-A1 | Modulators or Alpha7 Nicotinic Acetylcholine Receptors and Therapeutic Uses Thereof | SIENA BIOTECH S.P.A. (IT) | 2008-11-06 | — | — | US | disclosed |
| EP-1778658-A2 | MODULATORS OF ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTORS AND THERAPEUTIC USES THEREOF | Siena Biotech S.p.A. (IT) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006008133-A2 | MODULATORS OF ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTORS AND THERAPEUTIC USES THEREOF | SIENA BIOTECH S.P.A. (IT) | 2006-01-26 | — | — | WO | disclosed |
| EP-0277624-A2 | A composition comprising the addition product of a vinyl sulfone dye and a secondary amine and process for dyeing a polyamide therewith | HOECHST CELANESE CORPORATION (US) | 1988-08-10 | — | — | EP | disclosed |
| US-4762524-A | Composition comprising the addition product of a vinyl-sulfone dye and a secondary amine and process for dyeing a polyamide therewith | HOECHST CELANESE CORPORATION (US) | 1988-08-09 | — | — | US | disclosed |
| US-4082792-A | SECONDARY ALKYL PRIMARY AMINE, ALKENOIC ACID, PRIMARY OR SECONDARY ALCOHOL | TEXACO INC. (US) | 1978-04-04 | — | — | US | disclosed |
| US-3976682-A | ALKYLAMMONIUM ALKYLAMINOALKANOATES, FREEZE-THAW ADDITIVE, CORROSION INHIBITOR, PIGMENT GRINDING | TEXACO INC. (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275028-A1 | Modulators or Alpha7 Nicotinic Acetylcholine Receptors and Therapeutic Uses Thereof | CHRNA7, CHRNA5, CHRNA1 | MAPT 545/4885ABCC4 2398/4885TSHR 521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.