SCHEMBL8856051

SCHEMBL8856051

C=CCNCCCCC(=C)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.43
ALDH1A1 P00352 3/20 0.43
KMT2A Q03164 3/20 0.43
GAA P10253 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
TSHR P16473 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
LMNA P02545 1/20 0.40
MEN1 O00255 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
MAPT P10636 2/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
FAAH O00519 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16340122 0.98 KDM4E (0.42) KDM4EALDH1A1KMT2AGAANPC1
SCHEMBL1489810 0.94 KDM4E (0.40) KDM4EALDH1A1KMT2AGAANPC1
SCHEMBL1489418 0.86 ALOX15 (0.42) KDM4EALDH1A1KMT2AGAANPC1
SCHEMBL4928566 0.82 MAPT (0.52) KDM4EALDH1A1KMT2AGAANPC1
SCHEMBL3160520 0.81 MAPT (0.55) KDM4EALDH1A1KMT2AGAANPC1
SCHEMBL254214 0.81 MAPT (0.55) KDM4EALDH1A1KMT2AGAANPC1
SCHEMBL1073432 0.79 TSHR (0.39) KDM4EALDH1A1KMT2AGAANPC1
SCHEMBL2497943 0.77 PAOX (0.48) ALDH1A1KMT2ATSHRSMN1; SMN2LMNA
SCHEMBL636777 0.77 CYP2C19 (0.44) KMT2ATSHRMEN1CYP1A2CYP2C19
SCHEMBL4945287 0.77 ALOX15 (0.41) KDM4EALDH1A1KMT2ATSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10718960-B2 Method for producing contact lenses with wearing comfort ALCON INC. (CH) 2020-07-21 US disclosed
EP-3532276-A1 METHOD FOR PRODUCING SURFACE COATED CONTACT LENSES WITH WEARING COMFORT Novartis AG (CH) 2019-09-04 EP disclosed
EP-3344447-A1 METHOD FOR PRODUCING CONTACT LENSES WITH DURABLE LUBRICIOUS COATINGS THEREON Novartis AG (CH) 2018-07-11 EP disclosed
US-20180120590-A1 METHOD FOR PRODUCING CONTACT LENSES WITH WEARING COMFORT ALCON INC. (CH) 2018-05-03 US disclosed
US-9810812-B2 Method for producing contact lenses with durable lubricious coatings thereon NOVARTIS AG (CH) 2017-11-07 US disclosed
US-20170068019-A1 METHOD FOR PRODUCING CONTACT LENSES WITH DURABLE LUBRICIOUS COATINGS THEREON ALCON INC. (CH) 2017-03-09 US disclosed
EP-3013874-B1 ADDITIVE THAT IMPROVES ADHESION AND COATING COMPOUND CONTAINING THE SAME BYK CHEMIE GMBH (DE) 2016-12-14 EP disclosed
EP-3013874-A1 ADHESION-STRENGTHENING ADDITIVE AND COATING COMPOSITION CONTAINING SAME BYK-Chemie GmbH (DE) 2016-05-04 EP disclosed
WO-2014206962-A1 ADHESION-STRENGTHENING ADDITIVE AND COATING COMPOSITION CONTAINING SAME BYK-CHEMIE GMBH (DE) 2014-12-31 WO disclosed
US-5629066-A A COATED RESIN LAYER COVERING THE SURFACE OF FILM OR SHEET, IS MADE OF AN AMINO GROUP CONTAINING POLYMER AND/OR A POLYMER OF METHACRYLATE OF ISOCYANURIC ACID, HAVING AN EXPOSED SURFACE QUATERNIZED WITH ALKYL SULFATE OR SULFONATES TEIJIN LIMITED (JP) 1997-05-13 US disclosed
EP-0519420-B1 Resin article having anti-static property TEIJIN LTD (JP) 1995-12-20 EP disclosed
EP-0519420-A1 Resin article having anti-static property TEIJIN LIMITED (JP) 1992-12-23 EP disclosed